Abstract
The Kidney Disease: Improving Global Outcomes (KDIGO) Clinical Practice Guideline on Chronic Kidney Disease–Mineral and Bone Disorder (CKD–MBD) 2009 provided recommendations on the detection, evaluation, and treatment of CKD-MBD in patients CKD who are and are not undergoing dialysis. Because of the accumulation of evidence since this initial publication, the CKD-MBD Guideline underwent a selective update in 2017. In April 2018, KDIGO convened a CKD-MBD Guideline Implementation Summit in Japan with the key objective to discuss various barriers to the uptake and implementation of the CKD-MBD Guideline in 8 Asian countries/regions. These countries/regions were comparable according to their high-to-middle economic ranking assigned by the World Bank. The discussion took into account the availability of CKD-MBD medication therapies and government health policies that may influence reimbursement and practice patterns in the region. Most importantly, Summit participants developed a framework of multifaceted strategies aimed at overcoming barriers to guideline implementation. The Summit attendees suggested a shared decision-making approach between clinicians and patients in CKD-MBD management, as well as individualized care based on the treatment risk-benefit ratio. The Summit participants also discussed how KDIGO, as a guideline development organization, may work in partnership with local and national nephrology societies to provide education and facilitate implementation of the guideline by clinicians. The conclusions drawn from this Summit in Asia may serve as an important guide for other regions to follow.
Original language | English |
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Pages (from-to) | 1523-1537 |
Number of pages | 15 |
Journal | Kidney International Reports |
Volume | 4 |
Issue number | 11 |
DOIs | |
Publication status | Published - 2019 Nov |
Bibliographical note
Funding Information:This Summit conference was sponsored by KDIGO and supported in part by unrestricted educational grants from Bayer HealthCare, Boehringer Ingelheim, Chugai Pharmaceutical, Fresenius Medical Care, Japan CKD-MBD Forum, Japanese Society of Nephrology (JSN), Kissei Pharmaceutical, Kyowa Kirin Pharmaceutical Development, Nikkiso, Ono Pharmaceutical, Suntop Healthcare, and Torii Pharmaceutical. We thank Dr. Sinee Disthabanchong for valuable input into this manuscript. Other conference participants are Ali K. Abu-Alfa, Lebanon; Hideki Fujii, Japan; Naohiko Fujii, Japan; Kunitoshi Iseki, Japan; Nobuhiko Joki, Japan; Tilakavati Karupaiah, Malaysia; Naoki Kashihara, Japan; Junichiro Kazama, Japan; Fumihiko Koiwa, Japan; Hirotaka Komaba, Japan; Braden J. Manns, Canada; Masahide Mizobuchi, Japan; Yusuke Sakaguchi, Japan; Hiroko Segawa, Japan; Takashi Shigematsu, Japan; Tetsuo Shoji, Japan; Motoko Tanaka, Japan; Masatomo Taniguchi, Japan; Minako Wakasugi, Japan; and Suguru Yamamoto, Japan.
Publisher Copyright:
© 2019 International Society of Nephrology
Keywords
- CKD
- KDIGO CKD-MBD Guideline
- bone mineral density
- calcium
- dialysis
- hyperparathyroidism
- hyperphosphatemia
ASJC Scopus subject areas
- Nephrology