Abstract
Organoids have been attracting much attention in precision medicine research because they are formed similar to structures and constructs of human tissues and possess most of the genetic data. However, there is a problem that the current method of organoid culture is not suitable for high throughput screening. In this study, a high throughput screening model using organoids was presented and several colorectal cancer were analyzed based on this. The responses of the organoids to radiotherapy and chemotherapy was analyzed using this model, and the results were consistent with the genetic data of the organoids.
Original language | English |
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Title of host publication | 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 |
Publisher | Chemical and Biological Microsystems Society |
Pages | 420-421 |
Number of pages | 2 |
ISBN (Electronic) | 9781733419000 |
Publication status | Published - 2019 |
Event | 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 - Basel, Switzerland Duration: 2019 Oct 27 → 2019 Oct 31 |
Publication series
Name | 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 |
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Conference
Conference | 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 |
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Country/Territory | Switzerland |
City | Basel |
Period | 19/10/27 → 19/10/31 |
Bibliographical note
Funding Information:This work was supported by the Technology Innovation Program (10067407, Development of high throughput organoid clearing system and 3D imaging system for drug) funded By the Ministry of Trade, industry & Energy(MOTIE, Korea)
Publisher Copyright:
© 2019 CBMS-0001.
Keywords
- Chemotherapy
- High throughput screening
- Organoid
- Radiotherapy
- Uniform
ASJC Scopus subject areas
- Bioengineering
- Chemical Engineering (miscellaneous)