4'-O-Methylalpinumisoflavone inhibits the activation of monocytes/macrophages to an immunostimulatory phenotype induced by 27-hydroxycholesterol

Keyphrases

• Flavonoids 100%
• Monocyte-derived Macrophages 100%
• Immunostimulatory 100%
• 27-hydroxycholesterol 100%
• Phosphorylation 66%
• Carbon Tetrachloride 33%
• Cellular Level 33%
• Inflammatory Response 33%
• Induced Activation 33%
• P65 Subunit 33%
• Health Benefits 33%
• Lipopolysaccharide 33%
• Gene Products 33%
• Cholesterol 33%
• Isoflavones 33%
• Biological Activity 33%
• CD14 33%
• Matrix metalloproteinase-9 (MMP-9) 33%
• Nuclear factor-B 33%
• M1 Phenotype 33%
• Potential Gains 33%
• Chemokines 33%
• Monocytic Cells 33%
• THP-1 Cells 33%
• Disease Treatment 33%
• Cudrania Tricuspidata 33%
• Cell Effects 33%
• Matrix Product 33%
• Phenotype Markers 33%
• C-C Chemokine Receptor Type 5 (CCR5) 33%
• Chemokine (C-C motif) Ligand 2 (CCL2) 33%
• Surface Level 33%
• Maclura Tricuspidata 33%
• Plant Metabolites 33%
• Soluble CD14 (sCD14) 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Flavonoid 100%
• 26 Hydroxycholesterol 100%
• Chemokine 66%
• Disease 33%
• Inflammation 33%
• Isoflavone 33%
• Biological Activity 33%
• Alternative Complement Pathway C3 C5 Convertase 33%
• Gelatinase B 33%
• Nuclear Factor 33%
• Lipopolysaccharide 33%
• Chemokine Receptor 33%
• Maclura 33%

Immunology and Microbiology

• Macrophage 100%
• CD14 66%
• Chemokine 66%
• Secretion (Process) 33%
• Inflammation Response 33%
• Gene Product 33%
• Metabolite 33%
• Biological Activity 33%
• Chemokine Receptor 33%
• Complement Factor B 33%
• Maclura 33%