A biomemory chip composed of a myoglobin/CNT heterolayer fabricated by the protein-adsorption-precipitation-crosslinking (PAPC) technique

Jinho Yoon, Yong Ho Chung, Taek Lee, Jae Hyun Kim, Jungbae Kim, Jeong Woo Choi

    Research output: Contribution to journalArticlepeer-review

    6 Citations (Scopus)

    Abstract

    In this study, a biomemory chip consisting of a myoglobin/carbon nanotube (CNT) heterolayer is fabricated via the protein-adsorption-precipitation-crosslinking (PAPC) technique for electrochemical signal enhancement, long-term stability, and improved memory function. The PAPC technique is used to fabricate a myoglobin/CNT heterolayer with a CNT core and a high-density myoglobin-shell structure to achieve efficient heterolayer formation and improved performance of the heterolayer. The fabricated myoglobin/CNT heterolayer is immobilized onto a Au substrate through a chemical linker. The surface morphology of the deposited heterolayer is investigated via transmission electron microscopy and atomic force microscopy. The redox properties of the myoglobin/CNT heterolayer are investigated by cyclic voltammetry, and the memory function of the heterolayer, including the "write step" and "erase step," is measured by chronoamperometry. Compared with the myoglobin monolayer without CNT, the myoglobin/CNT heterolayer fabricated by the PAPC technique exhibits greater electrochemical signal enhancement, long-term stability at room temperature, and improved memory function. The results suggest that the proposed myoglobin/CNT heterolayer produced via the PAPC technique can be applied as a platform for bioelectronic devices to achieve improved signal intensity and durability.

    Original languageEnglish
    Pages (from-to)853-858
    Number of pages6
    JournalColloids and Surfaces B: Biointerfaces
    Volume136
    DOIs
    Publication statusPublished - 2015 Dec 1

    Bibliographical note

    Funding Information:
    This work was supported by the Samsung Research Funding Center of Samsung Electronics under Project Number SRFC-MA1401-04.

    Publisher Copyright:
    © 2015 Elsevier B.V.

    Copyright:
    Copyright 2015 Elsevier B.V., All rights reserved.

    Keywords

    • Biomemory chip
    • Carbon nanotubes
    • Electrochemical signal enhancement
    • Electrochemical signal stability
    • Protein-adsorption-precipitation-crosslinking (PAPC) technique

    ASJC Scopus subject areas

    • Biotechnology
    • Surfaces and Interfaces
    • Physical and Theoretical Chemistry
    • Colloid and Surface Chemistry

    Fingerprint

    Dive into the research topics of 'A biomemory chip composed of a myoglobin/CNT heterolayer fabricated by the protein-adsorption-precipitation-crosslinking (PAPC) technique'. Together they form a unique fingerprint.

    Cite this