TY - JOUR
T1 - A biomemory chip composed of a myoglobin/CNT heterolayer fabricated by the protein-adsorption-precipitation-crosslinking (PAPC) technique
AU - Yoon, Jinho
AU - Chung, Yong Ho
AU - Lee, Taek
AU - Kim, Jae Hyun
AU - Kim, Jungbae
AU - Choi, Jeong Woo
N1 - Funding Information:
This work was supported by the Samsung Research Funding Center of Samsung Electronics under Project Number SRFC-MA1401-04.
Publisher Copyright:
© 2015 Elsevier B.V.
Copyright:
Copyright 2015 Elsevier B.V., All rights reserved.
PY - 2015/12/1
Y1 - 2015/12/1
N2 - In this study, a biomemory chip consisting of a myoglobin/carbon nanotube (CNT) heterolayer is fabricated via the protein-adsorption-precipitation-crosslinking (PAPC) technique for electrochemical signal enhancement, long-term stability, and improved memory function. The PAPC technique is used to fabricate a myoglobin/CNT heterolayer with a CNT core and a high-density myoglobin-shell structure to achieve efficient heterolayer formation and improved performance of the heterolayer. The fabricated myoglobin/CNT heterolayer is immobilized onto a Au substrate through a chemical linker. The surface morphology of the deposited heterolayer is investigated via transmission electron microscopy and atomic force microscopy. The redox properties of the myoglobin/CNT heterolayer are investigated by cyclic voltammetry, and the memory function of the heterolayer, including the "write step" and "erase step," is measured by chronoamperometry. Compared with the myoglobin monolayer without CNT, the myoglobin/CNT heterolayer fabricated by the PAPC technique exhibits greater electrochemical signal enhancement, long-term stability at room temperature, and improved memory function. The results suggest that the proposed myoglobin/CNT heterolayer produced via the PAPC technique can be applied as a platform for bioelectronic devices to achieve improved signal intensity and durability.
AB - In this study, a biomemory chip consisting of a myoglobin/carbon nanotube (CNT) heterolayer is fabricated via the protein-adsorption-precipitation-crosslinking (PAPC) technique for electrochemical signal enhancement, long-term stability, and improved memory function. The PAPC technique is used to fabricate a myoglobin/CNT heterolayer with a CNT core and a high-density myoglobin-shell structure to achieve efficient heterolayer formation and improved performance of the heterolayer. The fabricated myoglobin/CNT heterolayer is immobilized onto a Au substrate through a chemical linker. The surface morphology of the deposited heterolayer is investigated via transmission electron microscopy and atomic force microscopy. The redox properties of the myoglobin/CNT heterolayer are investigated by cyclic voltammetry, and the memory function of the heterolayer, including the "write step" and "erase step," is measured by chronoamperometry. Compared with the myoglobin monolayer without CNT, the myoglobin/CNT heterolayer fabricated by the PAPC technique exhibits greater electrochemical signal enhancement, long-term stability at room temperature, and improved memory function. The results suggest that the proposed myoglobin/CNT heterolayer produced via the PAPC technique can be applied as a platform for bioelectronic devices to achieve improved signal intensity and durability.
KW - Biomemory chip
KW - Carbon nanotubes
KW - Electrochemical signal enhancement
KW - Electrochemical signal stability
KW - Protein-adsorption-precipitation-crosslinking (PAPC) technique
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U2 - 10.1016/j.colsurfb.2015.10.030
DO - 10.1016/j.colsurfb.2015.10.030
M3 - Article
C2 - 26539811
AN - SCOPUS:84946053265
SN - 0927-7765
VL - 136
SP - 853
EP - 858
JO - Colloids and Surfaces B: Biointerfaces
JF - Colloids and Surfaces B: Biointerfaces
ER -