Abstract
Fatness qualities in pigs measured by the amount of fat deposition and composition of fatty acids (FAs) in pork have considerable effect on current breeding goals. The stearoyl-CoA desaturase (SCD) gene plays a crucial role in the conversion of saturated FAs into monounsaturated FAs (MUFAs), and hence, is among the candidate genes responsible for pig fatness traits. Here, we identified a single nucleotide polymorphism (SNP, c.∗2041T>C) in the 3' untranslated region by direct sequencing focused on coding and regulatory regions of porcine SCD. According to the association analysis using a hundred of Berkshire pigs, the SNP was significantly associated with FA composition (MUFAs and polyunsaturated FAs [PUFAs]), polyunsaturated to saturated (P:S) FA ratio, n-6:n-3 FA ratio, and extent of fat deposition such as intramuscular fat and marbling (p<0.05). In addition, the SNP showed a significant effect on the SCD mRNA expression levels (p = 0.041). Based on our results, we suggest that the SCD c.∗2041T>C SNP plays a role in the gene regulation and affects the fatness qualities in Berkshire pigs.
Original language | English |
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Pages (from-to) | 151-157 |
Number of pages | 7 |
Journal | Asian-Australasian Journal of Animal Sciences |
Volume | 28 |
Issue number | 2 |
DOIs | |
Publication status | Published - 2015 Feb 1 |
Keywords
- Berkshire
- Fatness quality
- Polymorphism gene expression
- Stearoyl-CoA desaturase [SCD]
ASJC Scopus subject areas
- Food Science
- Animal Science and Zoology
- Engineering(all)