A carbazole based bimodal "turn-on" fluorescent probe for biothiols (cysteine/homocysteine) and fluoride: Sensing, imaging and its applications

Matinder Kaur, Byungkwon Yoon, Rajesh Kumar, Min Ju Cho, Hak Joong Kim, Jong Seung Kim, Dong Hoon Choi

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

A well-known carbazole-based precursor (probe 1) was used for the detection of cysteine/homocysteine and fluoride. Probe 1 shows a "turn-on" response to cysteine/homocysteine and fluoride via enhancement in emission intensity at 442 nm and 462 nm respectively, in solutions and living cells. Furthermore, probe 1 behaves as a fluorescent molecular switch between cysteine/homocysteine and fluoride as the chemical inputs, which have been used for the development of a combinatorial logic circuit and a molecular keypad lock.

Original languageEnglish
Pages (from-to)3437-3442
Number of pages6
JournalBulletin of the Korean Chemical Society
Volume35
Issue number12
DOIs
Publication statusPublished - 2014 Dec 20

Keywords

  • Bioimaging
  • Carbazole probe
  • Cysteine/homocysteine sensing
  • Fluoride recognition
  • Molecular keypad lock

ASJC Scopus subject areas

  • Chemistry(all)

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