A carbazole based bimodal "turn-on" fluorescent probe for biothiols (cysteine/homocysteine) and fluoride: Sensing, imaging and its applications

Matinder Kaur; Byungkwon Yoon; Rajesh Kumar; Min Ju Cho; Hak Joong Kim; Jong Seung Kim; Dong Hoon Choi

doi:10.5012/bkcs.2014.35.12.3437

A carbazole based bimodal "turn-on" fluorescent probe for biothiols (cysteine/homocysteine) and fluoride: Sensing, imaging and its applications

Matinder Kaur, Byungkwon Yoon, Rajesh Kumar, Min Ju Cho, Hak Joong Kim, Jong Seung Kim, Dong Hoon Choi

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

A well-known carbazole-based precursor (probe 1) was used for the detection of cysteine/homocysteine and fluoride. Probe 1 shows a "turn-on" response to cysteine/homocysteine and fluoride via enhancement in emission intensity at 442 nm and 462 nm respectively, in solutions and living cells. Furthermore, probe 1 behaves as a fluorescent molecular switch between cysteine/homocysteine and fluoride as the chemical inputs, which have been used for the development of a combinatorial logic circuit and a molecular keypad lock.

Original language	English
Pages (from-to)	3437-3442
Number of pages	6
Journal	Bulletin of the Korean Chemical Society
Volume	35
Issue number	12
DOIs	https://doi.org/10.5012/bkcs.2014.35.12.3437
Publication status	Published - 2014 Dec 20

Keywords

Bioimaging
Carbazole probe
Cysteine/homocysteine sensing
Fluoride recognition
Molecular keypad lock

ASJC Scopus subject areas

Chemistry(all)

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10.5012/bkcs.2014.35.12.3437

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title = "A carbazole based bimodal {"}turn-on{"} fluorescent probe for biothiols (cysteine/homocysteine) and fluoride: Sensing, imaging and its applications",

abstract = "A well-known carbazole-based precursor (probe 1) was used for the detection of cysteine/homocysteine and fluoride. Probe 1 shows a {"}turn-on{"} response to cysteine/homocysteine and fluoride via enhancement in emission intensity at 442 nm and 462 nm respectively, in solutions and living cells. Furthermore, probe 1 behaves as a fluorescent molecular switch between cysteine/homocysteine and fluoride as the chemical inputs, which have been used for the development of a combinatorial logic circuit and a molecular keypad lock.",

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T1 - A carbazole based bimodal "turn-on" fluorescent probe for biothiols (cysteine/homocysteine) and fluoride

T2 - Sensing, imaging and its applications

AU - Kaur, Matinder

AU - Yoon, Byungkwon

AU - Kumar, Rajesh

AU - Cho, Min Ju

AU - Kim, Hak Joong

AU - Kim, Jong Seung

AU - Choi, Dong Hoon

PY - 2014/12/20

Y1 - 2014/12/20

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AB - A well-known carbazole-based precursor (probe 1) was used for the detection of cysteine/homocysteine and fluoride. Probe 1 shows a "turn-on" response to cysteine/homocysteine and fluoride via enhancement in emission intensity at 442 nm and 462 nm respectively, in solutions and living cells. Furthermore, probe 1 behaves as a fluorescent molecular switch between cysteine/homocysteine and fluoride as the chemical inputs, which have been used for the development of a combinatorial logic circuit and a molecular keypad lock.

KW - Bioimaging

KW - Carbazole probe

KW - Cysteine/homocysteine sensing

KW - Fluoride recognition

KW - Molecular keypad lock

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VL - 35

SP - 3437

EP - 3442

JO - Bulletin of the Korean Chemical Society

JF - Bulletin of the Korean Chemical Society

IS - 12

ER -

A carbazole based bimodal "turn-on" fluorescent probe for biothiols (cysteine/homocysteine) and fluoride: Sensing, imaging and its applications

Abstract

Keywords

ASJC Scopus subject areas

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