A case of lymphocytic interstitial pneumonitis

H. J. Jung, E. R. Cho, J. J. Shim, K. H. In, S. H. Yu, K. H. Kang, N. H. Won, Y. H. Choi

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


Lymphocytic interstitial pneumonitis (LIP) is one of parenchymal pulmonary infiltrative diseases first described at 1966 by Carrington and Liebow. In LIP, there is a predominance of mature small lymphocytes in the interstitium of the lung which form germinal centers. The disease process surrounds, but dose not invade lung parenchyme, tracheobronchial tree and vascular structures. The etiology remains still unknown and the clinical features of this disorder have not been clearly defined. Therefore, the therapeutic modality is obscure. Development of LIP association with AIDS is often reported currently and possibility of progress to malignant lymphoma is emphasized. We experienced a case of primary LIP with pneumomediastinum. She was adimitted due to chest and anterior nuchal pain with chronic coughing, and diagnosed as pneumomediastinum with LIP. Medication with steroid was begun and some improvement of symptoms was observed, but an X-ray film of the chest remained same without improvement. We report above case with review of the literatures.

Original languageEnglish
Pages (from-to)602-609
Number of pages8
JournalTuberculosis and Respiratory Diseases
Issue number5
Publication statusPublished - 1993
Externally publishedYes


  • Lymphocytic Interstitial Pneumonitis (LIP)
  • malignant lymphoma
  • therapeutic modality

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Infectious Diseases


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