A case of nonclassifiable interstitial pneumonia after allogeneic hematopoietic stem cell transplantation

Ki Hwan Jung, Hwa Jung Sung, Ju Han Lee, Joungho Han, Chol Shin, Hyung Joo Park, Je Hyeong Kim

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Despite the improvements in supportive care, early and late hematopoietic stem cell transplantation-related complications still remain a significant cause of morbidity and mortality. Pulmonary complications occur in 40∼60% of patients who undergo allogeneic hematopoietic stem cell transplantation. Late-onset noninfectious pulmonary complications can occur months and even years after transplantation. Interstital lung disease has also been reported to be a late post-transplant complication. Exposure to cytotoxic drugs and/or irradiation has been implicated as a cause of pulmonary- toxicity including pulmonary fibrosis. We report a case of an 18-year-old female with non-classifiable interstitial pneumonia that manifested eight and a half years after allogeneic hematopoietic stem cell transplantation. The condition worsened rapidly and the patient eventually died.

    Original languageEnglish
    Pages (from-to)122-126
    Number of pages5
    JournalTuberculosis and Respiratory Diseases
    Volume66
    Issue number2
    DOIs
    Publication statusPublished - 2009 Feb

    Keywords

    • Hematopoietic stem cell transplantation
    • Interstitial lung disease
    • Pneumothorax

    ASJC Scopus subject areas

    • Pulmonary and Respiratory Medicine
    • Infectious Diseases

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