A case of pulmonary veno-occlusive disease

J. Y. Cho, S. Y. Lee, S. H. Lee, J. K. Suh, J. J. Shim, K. H. In, K. H. Kang, S. H. Yoo, K. T. Kim

Research output: Contribution to journalArticlepeer-review


Pulmonary veno-occlusive disease is a rare cause of pulmonary hypertension in which the primary abnormality is obliterative obstruction of pulmonary veins, especially venules. Clinically, we should suspect this disease in the case of congestive cardiac failure with pulmonary hypertension, chronic interstitial pulmonary edema, and normal or elevated wedge pressure on cardiac catheterization. We experience a case of pulmonary hypertension due to pulmonary veno-occlusive disease. A 55-year-old woman developed progressive dry cough and dyspnea for 3 months. Physical examination showed normal heart sounds, diffuse crackles in the whole lung fields. The liver was not palpable and pitting edema was absent. The diagnosis was made by chest HRCT, 2-D echocardiography, normal pulmonary capillary wedge pressure on cardiac catheterization, and confirmed by thoracoscopic lung biopsy. This patient was treated with vasodilator (calcium antagonist) and with mild symptomatic improvement. We reported a case of pulmonary veno-occlusive disease with review of literatures.

Original languageEnglish
Pages (from-to)274-279
Number of pages6
JournalTuberculosis and Respiratory Diseases
Issue number2
Publication statusPublished - 1996
Externally publishedYes


  • pulmonary hypertension
  • pulmonary veno-occlusive disease

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Infectious Diseases


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