Abstract
We have developed a trifunctional cleavable fluorescence turn-ON linker for chemoproteomic applications. This novel linker, which became highly fluorescent only upon cleavage of the azo bond, was successfully used for in situ proteome profiling/target identification and studies on newly synthesised proteomes.
Original language | English |
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Pages (from-to) | 13332-13335 |
Number of pages | 4 |
Journal | Chemical Communications |
Volume | 53 |
Issue number | 100 |
DOIs | |
Publication status | Published - 2017 |
Externally published | Yes |
Bibliographical note
Funding Information:Funding was provided by NMRC (CBRG/0038/2013), GSK-EDB Trust Fund (R-143-000-688-592), MOE-T1 (R-143-000-694-114) of Singapore, KIST (2E26110/CAP-16-02-KIST) and the Bio & Medical Technology Development Program of the National Research Foundation funded by the Ministry of Science, ICT & Future Planning (NRF-2016M3A9B6902060, NRF-2017M3A9D8029942) of Korea the and National Science Foundation of Zhejiang Province (LQ16B020003).
Publisher Copyright:
© 2017 The Royal Society of Chemistry.
ASJC Scopus subject areas
- Catalysis
- Electronic, Optical and Magnetic Materials
- Ceramics and Composites
- Chemistry(all)
- Surfaces, Coatings and Films
- Metals and Alloys
- Materials Chemistry