TY - GEN
T1 - A CMOS impedance cytometer for 3D flowing single-cell real-time analysis with ΔΣ error correction
AU - Lee, Kang Ho
AU - Nam, Jeonghun
AU - Choi, Sukhwan
AU - Lim, Hyunjung
AU - Shin, Sehyun
AU - Cho, Gyu Hyeong
PY - 2012
Y1 - 2012
N2 - Flow cytometry is an essential cell analysis technology in clinical immunology and haematology for the diagnosis and prognosis of disease. It involves the counting, identification and sorting of cells [1,2]. Conventional bulk measurements [3] require a large volume of blood, which is not desirable for the early detection of a disease, when only a very small percentage of cells contain evidence of the disease. In this paper, we propose, for the first time, a non-invasive and high-throughput single-cell analysis method using CMOS-integrated circuits in conjunction with a microfluidic channel as the first building block of a complete cell-sorting device.
AB - Flow cytometry is an essential cell analysis technology in clinical immunology and haematology for the diagnosis and prognosis of disease. It involves the counting, identification and sorting of cells [1,2]. Conventional bulk measurements [3] require a large volume of blood, which is not desirable for the early detection of a disease, when only a very small percentage of cells contain evidence of the disease. In this paper, we propose, for the first time, a non-invasive and high-throughput single-cell analysis method using CMOS-integrated circuits in conjunction with a microfluidic channel as the first building block of a complete cell-sorting device.
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U2 - 10.1109/ISSCC.2012.6177024
DO - 10.1109/ISSCC.2012.6177024
M3 - Conference contribution
AN - SCOPUS:84860676007
SN - 9781467303736
T3 - Digest of Technical Papers - IEEE International Solid-State Circuits Conference
SP - 304
EP - 305
BT - 2012 IEEE International Solid-State Circuits Conference, ISSCC 2012 - Digest of Technical Papers
T2 - 59th International Solid-State Circuits Conference, ISSCC 2012
Y2 - 19 February 2012 through 23 February 2012
ER -