A comprehensive karyotypic analysis on a newly established sarcomatoid hepatocellular carcinoma cell line SH-J1 by comparative genomic hybridization and chromosome painting

Dae Ghon Kim; Soo Yeun Park; Hyun Kim; Yong Hyuck Chun; Woo Sung Moon; Sun Hwa Park

doi:10.1016/S0165-4608(01)00543-X

A comprehensive karyotypic analysis on a newly established sarcomatoid hepatocellular carcinoma cell line SH-J1 by comparative genomic hybridization and chromosome painting

Dae Ghon Kim, Soo Yeun Park, Hyun Kim, Yong Hyuck Chun, Woo Sung Moon, Sun Hwa Park

Department of Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

27 Citations (Scopus)

Abstract

We first established a sarcomatoid hepatocellular carcinoma cell line, designated as SH-J1, and applied comparative genomic hybridization and fluorescence in situ hybridization (FISH) with chromosome painting probes for the characterization of the chromosomal rearrangements. In the SH-J1 cell line, the pleomorphic spindle cells were arranged in bundles of interlacing patterns and were positive in immunohistochemical staining with hepatocyte-related markers. By G-banding and FISH, the chromosomal gains were detected at 6p and 17, whereas losses were observed at 3p21∼pter, 3q27∼qter, 4, 6q, 13pter∼q11, 16, 18, 19p13, and Y.

Original language	English
Pages (from-to)	120-124
Number of pages	5
Journal	Cancer Genetics and Cytogenetics
Volume	132
Issue number	2
DOIs	https://doi.org/10.1016/S0165-4608(01)00543-X
Publication status	Published - 2002 Jan 15

Bibliographical note

Funding Information:
This work was supported by Grant 2000-0-210-003-3 from the Basic Research Program of the Korea Science and Engineering Foundation.

ASJC Scopus subject areas

Molecular Biology
Genetics
Cancer Research

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/S0165-4608(01)00543-X

Cite this

A comprehensive karyotypic analysis on a newly established sarcomatoid hepatocellular carcinoma cell line SH-J1 by comparative genomic hybridization and chromosome painting. / Kim, Dae Ghon; Park, Soo Yeun; Kim, Hyun et al.
In: Cancer Genetics and Cytogenetics, Vol. 132, No. 2, 15.01.2002, p. 120-124.

Research output: Contribution to journal › Article › peer-review

@article{803da0c51ba440fc9ba762a82667821d,

title = "A comprehensive karyotypic analysis on a newly established sarcomatoid hepatocellular carcinoma cell line SH-J1 by comparative genomic hybridization and chromosome painting",

abstract = "We first established a sarcomatoid hepatocellular carcinoma cell line, designated as SH-J1, and applied comparative genomic hybridization and fluorescence in situ hybridization (FISH) with chromosome painting probes for the characterization of the chromosomal rearrangements. In the SH-J1 cell line, the pleomorphic spindle cells were arranged in bundles of interlacing patterns and were positive in immunohistochemical staining with hepatocyte-related markers. By G-banding and FISH, the chromosomal gains were detected at 6p and 17, whereas losses were observed at 3p21∼pter, 3q27∼qter, 4, 6q, 13pter∼q11, 16, 18, 19p13, and Y.",

author = "Kim, {Dae Ghon} and Park, {Soo Yeun} and Hyun Kim and Chun, {Yong Hyuck} and Moon, {Woo Sung} and Park, {Sun Hwa}",

note = "Funding Information: This work was supported by Grant 2000-0-210-003-3 from the Basic Research Program of the Korea Science and Engineering Foundation.",

year = "2002",

month = jan,

day = "15",

doi = "10.1016/S0165-4608(01)00543-X",

language = "English",

volume = "132",

pages = "120--124",

journal = "Cancer Genetics and Cytogenetics",

issn = "0165-4608",

publisher = "Elsevier Inc.",

number = "2",

}

TY - JOUR

T1 - A comprehensive karyotypic analysis on a newly established sarcomatoid hepatocellular carcinoma cell line SH-J1 by comparative genomic hybridization and chromosome painting

AU - Kim, Dae Ghon

AU - Park, Soo Yeun

AU - Kim, Hyun

AU - Chun, Yong Hyuck

AU - Moon, Woo Sung

AU - Park, Sun Hwa

N1 - Funding Information: This work was supported by Grant 2000-0-210-003-3 from the Basic Research Program of the Korea Science and Engineering Foundation.

PY - 2002/1/15

Y1 - 2002/1/15

N2 - We first established a sarcomatoid hepatocellular carcinoma cell line, designated as SH-J1, and applied comparative genomic hybridization and fluorescence in situ hybridization (FISH) with chromosome painting probes for the characterization of the chromosomal rearrangements. In the SH-J1 cell line, the pleomorphic spindle cells were arranged in bundles of interlacing patterns and were positive in immunohistochemical staining with hepatocyte-related markers. By G-banding and FISH, the chromosomal gains were detected at 6p and 17, whereas losses were observed at 3p21∼pter, 3q27∼qter, 4, 6q, 13pter∼q11, 16, 18, 19p13, and Y.

AB - We first established a sarcomatoid hepatocellular carcinoma cell line, designated as SH-J1, and applied comparative genomic hybridization and fluorescence in situ hybridization (FISH) with chromosome painting probes for the characterization of the chromosomal rearrangements. In the SH-J1 cell line, the pleomorphic spindle cells were arranged in bundles of interlacing patterns and were positive in immunohistochemical staining with hepatocyte-related markers. By G-banding and FISH, the chromosomal gains were detected at 6p and 17, whereas losses were observed at 3p21∼pter, 3q27∼qter, 4, 6q, 13pter∼q11, 16, 18, 19p13, and Y.

UR - http://www.scopus.com/inward/record.url?scp=0037081848&partnerID=8YFLogxK

U2 - 10.1016/S0165-4608(01)00543-X

DO - 10.1016/S0165-4608(01)00543-X

M3 - Article

C2 - 11850072

AN - SCOPUS:0037081848

SN - 0165-4608

VL - 132

SP - 120

EP - 124

JO - Cancer Genetics and Cytogenetics

JF - Cancer Genetics and Cytogenetics

IS - 2

ER -

A comprehensive karyotypic analysis on a newly established sarcomatoid hepatocellular carcinoma cell line SH-J1 by comparative genomic hybridization and chromosome painting

Abstract

Bibliographical note

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this