Abstract
2,3-Disubstituted pyrrolo[2,3-b]pyridines were synthesized by palladium-catalyzed heteroannulation of 2-amino-3-iodopyridine derivatives and internal alkynes with Pd(OAc)2, LiCl, and KOAc in DMF. The 2-trimethylsilyl-3-methylpyrrolo[2,3-b]pyridine was transformed to 2-substituted-3-methylpyrrolo[2,3-b]pyridines.
Original language | English |
---|---|
Pages (from-to) | 627-630 |
Number of pages | 4 |
Journal | Tetrahedron Letters |
Volume | 39 |
Issue number | 7 |
DOIs | |
Publication status | Published - 1998 Feb 12 |
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry