A fluorescent rosamine compound selectively stains pluripotent stem cells

Chang Nim Im, Nam Young Kang, Hyung Ho Ha, Xuezhi Bi, Jae Jung Lee, Sung Jin Park, Sang Yeon Lee, Marc Vendrell, Yun Kyung Kim, Jun Seok Lee, Jun Li, Young Hoon Ahn, Bo Feng, Huck Hui Ng, Seong Wook Yun, Young Tae Chang

Research output: Contribution to journalArticlepeer-review

63 Citations (Scopus)

Abstract

The cell-by date: The fluorescent compound CDy1 selectively stains embryonic stem cells (see scheme). CDy1 was used to identify fibroblasts undergoing reprogramming to induced pluripotent stem cells prior to the expression of green fluorescent protein under the control of the Oct4 promoter.

Original languageEnglish
Pages (from-to)7497-7500
Number of pages4
JournalAngewandte Chemie - International Edition
Volume49
Issue number41
DOIs
Publication statusPublished - 2010 Oct 4
Externally publishedYes

Keywords

  • Cell recognition
  • Flurorescence
  • Imaging agents
  • Screening
  • Stem cells

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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