A highly sensitive two-photon fluorescent probe for mitochondrial Zinc ions in living tissue

Na Young Baek; Cheol Ho Heo; Chang Su Lim; Goutam Masanta; Bong Rae Cho; Hwan Myung Kim

doi:10.1039/c2cc31077e

A highly sensitive two-photon fluorescent probe for mitochondrial Zinc ions in living tissue

Na Young Baek, Cheol Ho Heo, Chang Su Lim, Goutam Masanta, Bong Rae Cho, Hwan Myung Kim

Research output: Contribution to journal › Article › peer-review

79 Citations (Scopus)

Abstract

We report a highly sensitive two-photon probe (SZn2-Mito) which shows a 70-fold two-photon excited fluorescence enhancement in response to Zn²⁺ and can selectively detect mitochondrial Zn²⁺ in a rat hippocampal slice at a depth of 100–200 μm by using two-photon microscopy.

Original language	English
Pages (from-to)	4546-4548
Number of pages	3
Journal	Chemical Communications
Volume	48
Issue number	38
DOIs	https://doi.org/10.1039/c2cc31077e
Publication status	Published - 2012 Apr 11

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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abstract = "We report a highly sensitive two-photon probe (SZn2-Mito) which shows a 70-fold two-photon excited fluorescence enhancement in response to Zn2+ and can selectively detect mitochondrial Zn2+ in a rat hippocampal slice at a depth of 100–200 μm by using two-photon microscopy.",

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AU - Baek, Na Young

AU - Heo, Cheol Ho

AU - Lim, Chang Su

AU - Masanta, Goutam

AU - Cho, Bong Rae

AU - Kim, Hwan Myung

PY - 2012/4/11

Y1 - 2012/4/11

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AB - We report a highly sensitive two-photon probe (SZn2-Mito) which shows a 70-fold two-photon excited fluorescence enhancement in response to Zn2+ and can selectively detect mitochondrial Zn2+ in a rat hippocampal slice at a depth of 100–200 μm by using two-photon microscopy.

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JO - Chemical Communications

JF - Chemical Communications

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A highly sensitive two-photon fluorescent probe for mitochondrial Zinc ions in living tissue

Abstract

ASJC Scopus subject areas

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