A human pluripotent stem cell line KUMi004-A generated from a patient with chronic lymphocytic leukemia

Ji Hea Kim; Ka Won Kang; Byung Hyun Lee; Young Park; Hwa Jung Sung; Byung Soo Kim

doi:10.1016/j.scr.2022.102668

A human pluripotent stem cell line KUMi004-A generated from a patient with chronic lymphocytic leukemia

Ji Hea Kim, Ka Won Kang, Byung Hyun Lee, Young Park, Hwa Jung Sung, Byung Soo Kim

Department of Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

Chronic lymphocytic leukemia (CLL) is a type of blood cancer caused by the abnormal accumulation of malignant plasma cells. In this study, we generated CLL iPSCs (KUMi004-a) using the Sendai virus, confirming pluripotency. Also, it can differentiate into three primary germ layers. We expect this cell line could be helpful to understand the pathology of CLL.

Original language	English
Article number	102668
Journal	Stem Cell Research
Volume	60
DOIs	https://doi.org/10.1016/j.scr.2022.102668
Publication status	Published - 2022 Apr

Bibliographical note

Funding Information:
This study was supported by the Bio & Medical Technology Development Program of the National Research Foundation, funded by the Ministry of Science and ICT (2017M3A9C8060403).

Funding Information:
The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Byung-Soo Kim reports financial support was provided by Korea Ministry of Science and ICT.

Publisher Copyright:
© 2022

ASJC Scopus subject areas

Developmental Biology
Cell Biology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.scr.2022.102668

Cite this

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title = "A human pluripotent stem cell line KUMi004-A generated from a patient with chronic lymphocytic leukemia",

abstract = "Chronic lymphocytic leukemia (CLL) is a type of blood cancer caused by the abnormal accumulation of malignant plasma cells. In this study, we generated CLL iPSCs (KUMi004-a) using the Sendai virus, confirming pluripotency. Also, it can differentiate into three primary germ layers. We expect this cell line could be helpful to understand the pathology of CLL.",

author = "Kim, {Ji Hea} and Kang, {Ka Won} and Lee, {Byung Hyun} and Young Park and {Jung Sung}, Hwa and Kim, {Byung Soo}",

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language = "English",

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AU - Kim, Ji Hea

AU - Kang, Ka Won

AU - Lee, Byung Hyun

AU - Park, Young

AU - Jung Sung, Hwa

AU - Kim, Byung Soo

N1 - Funding Information: This study was supported by the Bio & Medical Technology Development Program of the National Research Foundation, funded by the Ministry of Science and ICT (2017M3A9C8060403). Funding Information: The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Byung-Soo Kim reports financial support was provided by Korea Ministry of Science and ICT. Publisher Copyright: © 2022

PY - 2022/4

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N2 - Chronic lymphocytic leukemia (CLL) is a type of blood cancer caused by the abnormal accumulation of malignant plasma cells. In this study, we generated CLL iPSCs (KUMi004-a) using the Sendai virus, confirming pluripotency. Also, it can differentiate into three primary germ layers. We expect this cell line could be helpful to understand the pathology of CLL.

AB - Chronic lymphocytic leukemia (CLL) is a type of blood cancer caused by the abnormal accumulation of malignant plasma cells. In this study, we generated CLL iPSCs (KUMi004-a) using the Sendai virus, confirming pluripotency. Also, it can differentiate into three primary germ layers. We expect this cell line could be helpful to understand the pathology of CLL.

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ER -

A human pluripotent stem cell line KUMi004-A generated from a patient with chronic lymphocytic leukemia

Abstract

Bibliographical note

ASJC Scopus subject areas

UN SDGs

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