TY - JOUR
T1 - A mesoporous, silica-immobilized-nanoparticle colorimetric chemosensor for the detection of nerve agents
AU - Kim, Hyun Jung
AU - Lee, Ji Ha
AU - Lee, Hyejin
AU - Lee, Jae Hong
AU - Lee, Joung Hae
AU - Jung, Jong Hwa
AU - Kim, Jong Seung
PY - 2011/11/8
Y1 - 2011/11/8
N2 - A new and an easy-to-make colorimetric azo-pyridine, 1, and its recyclable mesoporous silica-immobilized nanoparticles for nerve-agent detection are synthesized. The binding site, comprising an azo-pyridine moiety, is capable of selectively sensing diethylchlorophosphate (DCP), one of the nerve-agent mimics of chemical-warfare agents, over a series of other phosphate compounds. Compound 1 shows ratiometric changes in absorption spectroscopy to the extent of a 60 nm red-shift upon the addition of DCP, mainly due to a change in the intramolecular charge transfer (ICT) in 1 . The color change of receptor 1 from yellow to red in the concentration region = 1.0 × 10 -6 M is sufficient for the selective detection of the DCP nerve-agent mimic by the naked eye. With regards to solid-phase application, mesoporous silica nanoparticles using 1 ( MSIAP ) are also prepared using a sol-gel grafting reaction. The color of the MSIAP also changes from red to yellow when dipped into an aqueous DCP solution, and turns back to red when treated with NaOH solution, with nontoxic diethylphosphoric acid being given off. The absorption changes of MSIAP in the presence of DCP are consistent within the 3-9 pH range.
AB - A new and an easy-to-make colorimetric azo-pyridine, 1, and its recyclable mesoporous silica-immobilized nanoparticles for nerve-agent detection are synthesized. The binding site, comprising an azo-pyridine moiety, is capable of selectively sensing diethylchlorophosphate (DCP), one of the nerve-agent mimics of chemical-warfare agents, over a series of other phosphate compounds. Compound 1 shows ratiometric changes in absorption spectroscopy to the extent of a 60 nm red-shift upon the addition of DCP, mainly due to a change in the intramolecular charge transfer (ICT) in 1 . The color change of receptor 1 from yellow to red in the concentration region = 1.0 × 10 -6 M is sufficient for the selective detection of the DCP nerve-agent mimic by the naked eye. With regards to solid-phase application, mesoporous silica nanoparticles using 1 ( MSIAP ) are also prepared using a sol-gel grafting reaction. The color of the MSIAP also changes from red to yellow when dipped into an aqueous DCP solution, and turns back to red when treated with NaOH solution, with nontoxic diethylphosphoric acid being given off. The absorption changes of MSIAP in the presence of DCP are consistent within the 3-9 pH range.
UR - http://www.scopus.com/inward/record.url?scp=82955207207&partnerID=8YFLogxK
U2 - 10.1002/adfm.201100968
DO - 10.1002/adfm.201100968
M3 - Article
AN - SCOPUS:82955207207
SN - 1616-301X
VL - 21
SP - 4035
EP - 4040
JO - Advanced Functional Materials
JF - Advanced Functional Materials
IS - 21
ER -