A mitochondria-localized two-photon fluorescent probe for ratiometric imaging of hydrogen peroxide in live tissue

Goutam Masanta; Cheol Ho Heo; Chang Su Lim; Sung Keun Bae; Bong Rae Cho; Hwan Myung Kim

doi:10.1039/c2cc00034b

A mitochondria-localized two-photon fluorescent probe for ratiometric imaging of hydrogen peroxide in live tissue

Goutam Masanta, Cheol Ho Heo, Chang Su Lim, Sung Keun Bae, Bong Rae Cho, Hwan Myung Kim

* Honorary professors

Research output: Contribution to journal › Article › peer-review

153 Citations (Scopus)

Abstract

We report a two-photon fluorescent probe (SHP-Mito) which can ratiometrically detect mitochondrial H₂O₂ in live cells and intact tissues at >100 μm depth through the use of two-photon microscopy.

Original language	English
Pages (from-to)	3518-3520
Number of pages	3
Journal	Chemical Communications
Volume	48
Issue number	29
DOIs	https://doi.org/10.1039/c2cc00034b
Publication status	Published - 2012 Mar 12

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Chemistry(all)
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/c2cc00034b

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title = "A mitochondria-localized two-photon fluorescent probe for ratiometric imaging of hydrogen peroxide in live tissue",

abstract = "We report a two-photon fluorescent probe (SHP-Mito) which can ratiometrically detect mitochondrial H2O2 in live cells and intact tissues at >100 μm depth through the use of two-photon microscopy.",

author = "Goutam Masanta and Heo, {Cheol Ho} and Lim, {Chang Su} and Bae, {Sung Keun} and Cho, {Bong Rae} and Kim, {Hwan Myung}",

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AU - Masanta, Goutam

AU - Heo, Cheol Ho

AU - Lim, Chang Su

AU - Bae, Sung Keun

AU - Cho, Bong Rae

AU - Kim, Hwan Myung

PY - 2012/3/12

Y1 - 2012/3/12

N2 - We report a two-photon fluorescent probe (SHP-Mito) which can ratiometrically detect mitochondrial H2O2 in live cells and intact tissues at >100 μm depth through the use of two-photon microscopy.

AB - We report a two-photon fluorescent probe (SHP-Mito) which can ratiometrically detect mitochondrial H2O2 in live cells and intact tissues at >100 μm depth through the use of two-photon microscopy.

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EP - 3520

JO - Chemical Communications

JF - Chemical Communications

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ER -

A mitochondria-localized two-photon fluorescent probe for ratiometric imaging of hydrogen peroxide in live tissue

Abstract

ASJC Scopus subject areas

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