A mitochondria-localized two-photon fluorescent probe for ratiometric imaging of hydrogen peroxide in live tissue

Goutam Masanta; Cheol Ho Heo; Chang Su Lim; Sung Keun Bae; Bong Rae Cho; Hwan Myung Kim

doi:10.1039/c2cc00034b

A mitochondria-localized two-photon fluorescent probe for ratiometric imaging of hydrogen peroxide in live tissue

Goutam Masanta, Cheol Ho Heo, Chang Su Lim, Sung Keun Bae, Bong Rae Cho, Hwan Myung Kim

Research output: Contribution to journal › Article › peer-review

157 Citations (Scopus)

Abstract

We report a two-photon fluorescent probe (SHP-Mito) which can ratiometrically detect mitochondrial H₂O₂ in live cells and intact tissues at >100 μm depth through the use of two-photon microscopy.

Original language	English
Pages (from-to)	3518-3520
Number of pages	3
Journal	Chemical Communications
Volume	48
Issue number	29
DOIs	https://doi.org/10.1039/c2cc00034b
Publication status	Published - 2012 Mar 12

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/c2cc00034b

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title = "A mitochondria-localized two-photon fluorescent probe for ratiometric imaging of hydrogen peroxide in live tissue",

abstract = "We report a two-photon fluorescent probe (SHP-Mito) which can ratiometrically detect mitochondrial H2O2 in live cells and intact tissues at >100 μm depth through the use of two-photon microscopy.",

author = "Goutam Masanta and Heo, {Cheol Ho} and Lim, {Chang Su} and Bae, {Sung Keun} and Cho, {Bong Rae} and Kim, {Hwan Myung}",

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doi = "10.1039/c2cc00034b",

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AU - Masanta, Goutam

AU - Heo, Cheol Ho

AU - Lim, Chang Su

AU - Bae, Sung Keun

AU - Cho, Bong Rae

AU - Kim, Hwan Myung

PY - 2012/3/12

Y1 - 2012/3/12

N2 - We report a two-photon fluorescent probe (SHP-Mito) which can ratiometrically detect mitochondrial H2O2 in live cells and intact tissues at >100 μm depth through the use of two-photon microscopy.

AB - We report a two-photon fluorescent probe (SHP-Mito) which can ratiometrically detect mitochondrial H2O2 in live cells and intact tissues at >100 μm depth through the use of two-photon microscopy.

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EP - 3520

JO - Chemical Communications

JF - Chemical Communications

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ER -

A mitochondria-localized two-photon fluorescent probe for ratiometric imaging of hydrogen peroxide in live tissue

Abstract

ASJC Scopus subject areas

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