A new efficient synthesis of Ro-31-6930, a potent potassium channel activator, and its analogs

Sung eun Yoo; Jee Hee Suh; Sang Jo Lee; Nakcheol Jeong

doi:10.1016/S0960-894X(00)80150-X

A new efficient synthesis of Ro-31-6930, a potent potassium channel activator, and its analogs

Sung eun Yoo, Jee Hee Suh, Sang Jo Lee, Nakcheol Jeong

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

A potent potassium channel activator, Ro-31-6930 and its analogs were prepared efficiently by employing Pd(O) mediated coupling of the appropriate enol triflates and pyridine (tributyl) tin.

Original language	English
Pages (from-to)	381-382
Number of pages	2
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	2
Issue number	5
DOIs	https://doi.org/10.1016/S0960-894X(00)80150-X
Publication status	Published - 1992

ASJC Scopus subject areas

Biochemistry
Molecular Medicine
Molecular Biology
Pharmaceutical Science
Drug Discovery
Clinical Biochemistry
Organic Chemistry

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title = "A new efficient synthesis of Ro-31-6930, a potent potassium channel activator, and its analogs",

abstract = "A potent potassium channel activator, Ro-31-6930 and its analogs were prepared efficiently by employing Pd(O) mediated coupling of the appropriate enol triflates and pyridine (tributyl) tin.",

author = "Yoo, {Sung eun} and Suh, {Jee Hee} and Lee, {Sang Jo} and Nakcheol Jeong",

year = "1992",

doi = "10.1016/S0960-894X(00)80150-X",

language = "English",

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T1 - A new efficient synthesis of Ro-31-6930, a potent potassium channel activator, and its analogs

AU - Yoo, Sung eun

AU - Suh, Jee Hee

AU - Lee, Sang Jo

AU - Jeong, Nakcheol

PY - 1992

Y1 - 1992

N2 - A potent potassium channel activator, Ro-31-6930 and its analogs were prepared efficiently by employing Pd(O) mediated coupling of the appropriate enol triflates and pyridine (tributyl) tin.

AB - A potent potassium channel activator, Ro-31-6930 and its analogs were prepared efficiently by employing Pd(O) mediated coupling of the appropriate enol triflates and pyridine (tributyl) tin.

UR - http://www.scopus.com/inward/record.url?scp=0026731212&partnerID=8YFLogxK

U2 - 10.1016/S0960-894X(00)80150-X

DO - 10.1016/S0960-894X(00)80150-X

M3 - Article

AN - SCOPUS:0026731212

SN - 0960-894X

VL - 2

SP - 381

EP - 382

JO - Bioorganic and Medicinal Chemistry Letters

JF - Bioorganic and Medicinal Chemistry Letters

IS - 5

ER -

A new efficient synthesis of Ro-31-6930, a potent potassium channel activator, and its analogs

Abstract

ASJC Scopus subject areas

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