A new homogeneity index based on statistical analysis of the dose-volume histogram

Myonggeun Yoon; Sung Yong Park; Dongho Shin; Se Byeong Lee; Hong Ryull Pyo; Dae Yong Kim; Kwan Ho Cho

doi:10.1120/jacmp.v8i2.2390

A new homogeneity index based on statistical analysis of the dose-volume histogram

Myonggeun Yoon, Sung Yong Park, Dongho Shin, Se Byeong Lee, Hong Ryull Pyo, Dae Yong Kim, Kwan Ho Cho

Research output: Contribution to journal › Article › peer-review

115 Citations (Scopus)

Abstract

The goal of the present study was to develop a new dose-volume histogram (DVH)- based homogeneity index for effectively evaluating the dose homogeneity of intensity-modulated radiotherapy plans. The new index, called the sigma-index ("S-index") is defined as the standard deviation of the normalized differential DVH curve. In a study of 16 patients with brain tumors at our institution, the S-index was found to vary from 0.80 to 3.15. Our results showed that the S-index provides a more reliable and accurate measure of dose homogeneity than that given by conventional methods. A guideline for evaluating the dose homogeneity of treatment plans based on the S-index and its relation to equivalent uniform dose is discussed.

Original language	English
Pages (from-to)	9-17
Number of pages	9
Journal	Journal of Applied Clinical Medical Physics
Volume	8
Issue number	2
DOIs	https://doi.org/10.1120/jacmp.v8i2.2390
Publication status	Published - 2007
Externally published	Yes

Keywords

Dose-volume histogram
Equivalent uniform dose
Homogeneity index
Intensity-modulated radiotherapy

ASJC Scopus subject areas

Radiation
Instrumentation
Radiology Nuclear Medicine and imaging

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10.1120/jacmp.v8i2.2390

Cite this

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AU - Yoon, Myonggeun

AU - Park, Sung Yong

AU - Shin, Dongho

AU - Lee, Se Byeong

AU - Pyo, Hong Ryull

AU - Kim, Dae Yong

AU - Cho, Kwan Ho

PY - 2007

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A new homogeneity index based on statistical analysis of the dose-volume histogram

Abstract

Keywords

ASJC Scopus subject areas

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