A new in vivo-mimic angiogenesis MI-crofluidc platfrom for the study of cell encapsulation based cell therapy

Choong Kim, Min Cheol Kim, Seok Chung, H. Harry Asada, Roger D. Kamm

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Abstract

    In this paper, we have developed a novel in vitro angiogenesis on a chip to identify potential molecular targets, secreted from cell encapsulated beads; augmenting, altering and blocking endothelial cell responses, and to enable preliminary screening before transplantation. We confirmed that growth factors secreted from the encapsulated cells in CE beads were able to induce ECs migration and form lumen-like structures in the collagen scaffold.

    Original languageEnglish
    Title of host publication15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
    Pages783-785
    Number of pages3
    Publication statusPublished - 2011
    Event15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011 - Seattle, WA, United States
    Duration: 2011 Oct 22011 Oct 6

    Publication series

    Name15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
    Volume2

    Other

    Other15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
    Country/TerritoryUnited States
    CitySeattle, WA
    Period11/10/211/10/6

    Keywords

    • Angiogenesis
    • Cell encapsulation based cell therapy

    ASJC Scopus subject areas

    • Control and Systems Engineering

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