A new MEMS neural probe system integrated with push-pull microfluidic channels and biosensors for real-time monitoring of neurochemicals

Uikyu Chae, Hyoguen Shin, Hyunjoo Jenny Lee, Jungpyo Lee, Nakwon Choi, Yi Jae Lee, Soo Hyun Lee, Jiwan Woo, Yakdol Cho, Eui Sung Yoon, Hyun Yong Yu, Il Joo Cho

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    2 Citations (Scopus)

    Abstract

    We present a new MEMS neural probe integrated with two microfluidic channels, a mixer, and biosensors for real-time monitoring of neurochemicals and neural activities. The microfluidic channels for push-pull operation of fluids enable infusion of drugs and extraction of brain fluid at the same time. Also, we can simultaneously monitor neural activities modulated by the infused drug. The real-time monitoring of neurochemicals using the monolithically integrated sensors is a new concept we propose which is enabled through the MEMS technology. The proposed system will provide an important new set of information for brain disease investigation and functional brain-mapping.

    Original languageEnglish
    Title of host publicationMEMS 2016 - 29th IEEE International Conference on Micro Electro Mechanical Systems
    PublisherInstitute of Electrical and Electronics Engineers Inc.
    Pages329-332
    Number of pages4
    ISBN (Electronic)9781509019731
    DOIs
    Publication statusPublished - 2016 Feb 26
    Event29th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2016 - Shanghai, China
    Duration: 2016 Jan 242016 Jan 28

    Publication series

    NameProceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
    Volume2016-February
    ISSN (Print)1084-6999

    Other

    Other29th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2016
    Country/TerritoryChina
    CityShanghai
    Period16/1/2416/1/28

    Bibliographical note

    Publisher Copyright:
    © 2016 IEEE.

    ASJC Scopus subject areas

    • Electronic, Optical and Magnetic Materials
    • Condensed Matter Physics
    • Mechanical Engineering
    • Electrical and Electronic Engineering

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