A new risk score system for the assessment of clinical outcomes in patients with non-ST-segment elevation myocardial infarction

Hyun Kuk Kim; Myung Ho Jeong; Youngkeun Ahn; Jong Hyun Kim; Shung Chull Chae; Young Jo Kim; Seung Ho Hur; In Whan Seong; Taek Jong Hong; Dong Hoon Choi; Myeong Chan Cho; Chong Jin Kim; Ki Bae Seung; Wook Sung Chung; Yang Soo Jang; Seung Woon Rha; Jang Ho Bae; Jeong Gwan Cho; Seung Jung Park

doi:10.1016/j.ijcard.2009.06.001

A new risk score system for the assessment of clinical outcomes in patients with non-ST-segment elevation myocardial infarction

Hyun Kuk Kim, Myung Ho Jeong, Youngkeun Ahn, Jong Hyun Kim, Shung Chull Chae, Young Jo Kim, Seung Ho Hur, In Whan Seong, Taek Jong Hong, Dong Hoon Choi, Myeong Chan Cho, Chong Jin Kim, Ki Bae Seung, Wook Sung Chung, Yang Soo Jang, Seung Woon Rha, Jang Ho Bae, Jeong Gwan Cho, Seung Jung Park

Research output: Contribution to journal › Article › peer-review

27 Citations (Scopus)

Abstract

Background and objectives: Prediction for long-term clinical outcomes in patients with non-ST elevation acute coronary syndrome is important as well as early risk stratification. The aim of this study is to develop a simple assessment tool for better early bedside risk stratification for both short- and long-term clinical outcomes. Subjects and methods: 2148 patients with non-ST-segment elevation myocardial infarction (NSTEMI) (64.9 ±12.2 years, 35.0% females) were enrolled in a nationwide prospective Korea Acute Myocardial Infarction Registry (KAMIR). A new risk score was constructed using the variables related to one year mortality: TIMI risk index (17.5-30: 1 point, > 30: 2 points), Killip class (II: 1 point, > II: 2 points) and serum creatinine (? 1.5 mg/dL: 1 point), based on the multivariate-adjusted risk relationship. The new risk score system was compared with the Global Registry of Acute Coronary Events (GRACE) and TIMI risk scores during a 12-month clinical follow-up. Results: During a one year follow-up, all causes of death occurred in 362 patients (14.3%), and 184 (8.6%) patients died in the hospital. The new risk score showed good predictive value for one year mortality. The accuracy for in-hospital and one year post-discharge mortality rates, the new risk score demonstrated significant differences in predictive accuracy when compared with TIMI and GRACE risk scores. Conclusion: A new risk score in the present study provides simplicity with accuracy simultaneously for early risk stratification, and also could be a powerful predictive tool for long-term prognosis in NSTEMI.

Original language	English
Pages (from-to)	450-454
Number of pages	5
Journal	International Journal of Cardiology
Volume	145
Issue number	3
DOIs	https://doi.org/10.1016/j.ijcard.2009.06.001
Publication status	Published - 2010 Dec 3

Bibliographical note

Funding Information:
This study was performed with the support of the Korean Circulation Society (KCS) as a memorandum of the 50th Anniversary of the KCS. The authors of this manuscript have certified that they comply with the Principles of Ethical Publishing in the International Journal of Cardiology [25] . Appendix A KAMIR Investigators: Myung Ho Jeong, Young Jo Kim, Chong Jin Kim, Myeong Chan Cho, Youngkeun Ahn, Jong Hyun Kim, Shung Chull Chae, Seung Ho Hur, In Whan Seong, Taek Jong Hong, Donghoon Choi, Jei Keon Chae, Jay Young Rhew, Doo Il Kim, In Ho Chae, Junghan Yoon, Bon Kwon Koo, Byung Ok Kim, Myoung Yong Lee, Kee Sik Kim, Jin Yong Hwang, Seok Kyu Oh, Nae Hee Lee, Kyoung Tae Jeong, Seung Jea Tahk, Jang Ho Bae, Seung Woon Rha, Keum Soo Park, Kyoo Rok Han, Tae Hoon Ahn, Moo Hyun Kim, Joo Young Yang, Chong Yun Rhim, Hyeon Cheol Gwon, Seong Wook Park, Young Youp Koh, Seung Jae Joo, Soo Joong Kim, Dong Kyu Jin, Jin Man Cho, Wook Sung Chung, Yang Soo Jang, Jeong Gwan Cho, Ki Bae Seung and Seung Jung Park.

Keywords

Myocardial infarction
Prognosis
Risk factors

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1016/j.ijcard.2009.06.001

Cite this

Kim, H. K., Jeong, M. H., Ahn, Y., Kim, J. H., Chae, S. C., Kim, Y. J., Hur, S. H., Seong, I. W., Hong, T. J., Choi, D. H., Cho, M. C., Kim, C. J., Seung, K. B., Chung, W. S., Jang, Y. S., Rha, S. W., Bae, J. H., Cho, J. G., & Park, S. J. (2010). A new risk score system for the assessment of clinical outcomes in patients with non-ST-segment elevation myocardial infarction. International Journal of Cardiology, 145(3), 450-454. https://doi.org/10.1016/j.ijcard.2009.06.001

Kim, HK, Jeong, MH, Ahn, Y, Kim, JH, Chae, SC, Kim, YJ, Hur, SH, Seong, IW, Hong, TJ, Choi, DH, Cho, MC, Kim, CJ, Seung, KB, Chung, WS, Jang, YS, Rha, SW, Bae, JH, Cho, JG & Park, SJ 2010, 'A new risk score system for the assessment of clinical outcomes in patients with non-ST-segment elevation myocardial infarction', International Journal of Cardiology, vol. 145, no. 3, pp. 450-454. https://doi.org/10.1016/j.ijcard.2009.06.001

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title = "A new risk score system for the assessment of clinical outcomes in patients with non-ST-segment elevation myocardial infarction",

abstract = "Background and objectives: Prediction for long-term clinical outcomes in patients with non-ST elevation acute coronary syndrome is important as well as early risk stratification. The aim of this study is to develop a simple assessment tool for better early bedside risk stratification for both short- and long-term clinical outcomes. Subjects and methods: 2148 patients with non-ST-segment elevation myocardial infarction (NSTEMI) (64.9 ±12.2 years, 35.0% females) were enrolled in a nationwide prospective Korea Acute Myocardial Infarction Registry (KAMIR). A new risk score was constructed using the variables related to one year mortality: TIMI risk index (17.5-30: 1 point, > 30: 2 points), Killip class (II: 1 point, > II: 2 points) and serum creatinine (? 1.5 mg/dL: 1 point), based on the multivariate-adjusted risk relationship. The new risk score system was compared with the Global Registry of Acute Coronary Events (GRACE) and TIMI risk scores during a 12-month clinical follow-up. Results: During a one year follow-up, all causes of death occurred in 362 patients (14.3%), and 184 (8.6%) patients died in the hospital. The new risk score showed good predictive value for one year mortality. The accuracy for in-hospital and one year post-discharge mortality rates, the new risk score demonstrated significant differences in predictive accuracy when compared with TIMI and GRACE risk scores. Conclusion: A new risk score in the present study provides simplicity with accuracy simultaneously for early risk stratification, and also could be a powerful predictive tool for long-term prognosis in NSTEMI.",

keywords = "Myocardial infarction, Prognosis, Risk factors",

author = "Kim, {Hyun Kuk} and Jeong, {Myung Ho} and Youngkeun Ahn and Kim, {Jong Hyun} and Chae, {Shung Chull} and Kim, {Young Jo} and Hur, {Seung Ho} and Seong, {In Whan} and Hong, {Taek Jong} and Choi, {Dong Hoon} and Cho, {Myeong Chan} and Kim, {Chong Jin} and Seung, {Ki Bae} and Chung, {Wook Sung} and Jang, {Yang Soo} and Rha, {Seung Woon} and Bae, {Jang Ho} and Cho, {Jeong Gwan} and Park, {Seung Jung}",

note = "Funding Information: This study was performed with the support of the Korean Circulation Society (KCS) as a memorandum of the 50th Anniversary of the KCS. The authors of this manuscript have certified that they comply with the Principles of Ethical Publishing in the International Journal of Cardiology [25] . Appendix A KAMIR Investigators: Myung Ho Jeong, Young Jo Kim, Chong Jin Kim, Myeong Chan Cho, Youngkeun Ahn, Jong Hyun Kim, Shung Chull Chae, Seung Ho Hur, In Whan Seong, Taek Jong Hong, Donghoon Choi, Jei Keon Chae, Jay Young Rhew, Doo Il Kim, In Ho Chae, Junghan Yoon, Bon Kwon Koo, Byung Ok Kim, Myoung Yong Lee, Kee Sik Kim, Jin Yong Hwang, Seok Kyu Oh, Nae Hee Lee, Kyoung Tae Jeong, Seung Jea Tahk, Jang Ho Bae, Seung Woon Rha, Keum Soo Park, Kyoo Rok Han, Tae Hoon Ahn, Moo Hyun Kim, Joo Young Yang, Chong Yun Rhim, Hyeon Cheol Gwon, Seong Wook Park, Young Youp Koh, Seung Jae Joo, Soo Joong Kim, Dong Kyu Jin, Jin Man Cho, Wook Sung Chung, Yang Soo Jang, Jeong Gwan Cho, Ki Bae Seung and Seung Jung Park. ",

year = "2010",

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doi = "10.1016/j.ijcard.2009.06.001",

language = "English",

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T1 - A new risk score system for the assessment of clinical outcomes in patients with non-ST-segment elevation myocardial infarction

AU - Kim, Hyun Kuk

AU - Jeong, Myung Ho

AU - Ahn, Youngkeun

AU - Kim, Jong Hyun

AU - Chae, Shung Chull

AU - Kim, Young Jo

AU - Hur, Seung Ho

AU - Seong, In Whan

AU - Hong, Taek Jong

AU - Choi, Dong Hoon

AU - Cho, Myeong Chan

AU - Kim, Chong Jin

AU - Seung, Ki Bae

AU - Chung, Wook Sung

AU - Jang, Yang Soo

AU - Rha, Seung Woon

AU - Bae, Jang Ho

AU - Cho, Jeong Gwan

AU - Park, Seung Jung

N1 - Funding Information: This study was performed with the support of the Korean Circulation Society (KCS) as a memorandum of the 50th Anniversary of the KCS. The authors of this manuscript have certified that they comply with the Principles of Ethical Publishing in the International Journal of Cardiology [25] . Appendix A KAMIR Investigators: Myung Ho Jeong, Young Jo Kim, Chong Jin Kim, Myeong Chan Cho, Youngkeun Ahn, Jong Hyun Kim, Shung Chull Chae, Seung Ho Hur, In Whan Seong, Taek Jong Hong, Donghoon Choi, Jei Keon Chae, Jay Young Rhew, Doo Il Kim, In Ho Chae, Junghan Yoon, Bon Kwon Koo, Byung Ok Kim, Myoung Yong Lee, Kee Sik Kim, Jin Yong Hwang, Seok Kyu Oh, Nae Hee Lee, Kyoung Tae Jeong, Seung Jea Tahk, Jang Ho Bae, Seung Woon Rha, Keum Soo Park, Kyoo Rok Han, Tae Hoon Ahn, Moo Hyun Kim, Joo Young Yang, Chong Yun Rhim, Hyeon Cheol Gwon, Seong Wook Park, Young Youp Koh, Seung Jae Joo, Soo Joong Kim, Dong Kyu Jin, Jin Man Cho, Wook Sung Chung, Yang Soo Jang, Jeong Gwan Cho, Ki Bae Seung and Seung Jung Park.

PY - 2010/12/3

Y1 - 2010/12/3

N2 - Background and objectives: Prediction for long-term clinical outcomes in patients with non-ST elevation acute coronary syndrome is important as well as early risk stratification. The aim of this study is to develop a simple assessment tool for better early bedside risk stratification for both short- and long-term clinical outcomes. Subjects and methods: 2148 patients with non-ST-segment elevation myocardial infarction (NSTEMI) (64.9 ±12.2 years, 35.0% females) were enrolled in a nationwide prospective Korea Acute Myocardial Infarction Registry (KAMIR). A new risk score was constructed using the variables related to one year mortality: TIMI risk index (17.5-30: 1 point, > 30: 2 points), Killip class (II: 1 point, > II: 2 points) and serum creatinine (? 1.5 mg/dL: 1 point), based on the multivariate-adjusted risk relationship. The new risk score system was compared with the Global Registry of Acute Coronary Events (GRACE) and TIMI risk scores during a 12-month clinical follow-up. Results: During a one year follow-up, all causes of death occurred in 362 patients (14.3%), and 184 (8.6%) patients died in the hospital. The new risk score showed good predictive value for one year mortality. The accuracy for in-hospital and one year post-discharge mortality rates, the new risk score demonstrated significant differences in predictive accuracy when compared with TIMI and GRACE risk scores. Conclusion: A new risk score in the present study provides simplicity with accuracy simultaneously for early risk stratification, and also could be a powerful predictive tool for long-term prognosis in NSTEMI.

AB - Background and objectives: Prediction for long-term clinical outcomes in patients with non-ST elevation acute coronary syndrome is important as well as early risk stratification. The aim of this study is to develop a simple assessment tool for better early bedside risk stratification for both short- and long-term clinical outcomes. Subjects and methods: 2148 patients with non-ST-segment elevation myocardial infarction (NSTEMI) (64.9 ±12.2 years, 35.0% females) were enrolled in a nationwide prospective Korea Acute Myocardial Infarction Registry (KAMIR). A new risk score was constructed using the variables related to one year mortality: TIMI risk index (17.5-30: 1 point, > 30: 2 points), Killip class (II: 1 point, > II: 2 points) and serum creatinine (? 1.5 mg/dL: 1 point), based on the multivariate-adjusted risk relationship. The new risk score system was compared with the Global Registry of Acute Coronary Events (GRACE) and TIMI risk scores during a 12-month clinical follow-up. Results: During a one year follow-up, all causes of death occurred in 362 patients (14.3%), and 184 (8.6%) patients died in the hospital. The new risk score showed good predictive value for one year mortality. The accuracy for in-hospital and one year post-discharge mortality rates, the new risk score demonstrated significant differences in predictive accuracy when compared with TIMI and GRACE risk scores. Conclusion: A new risk score in the present study provides simplicity with accuracy simultaneously for early risk stratification, and also could be a powerful predictive tool for long-term prognosis in NSTEMI.

KW - Myocardial infarction

KW - Prognosis

KW - Risk factors

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A new risk score system for the assessment of clinical outcomes in patients with non-ST-segment elevation myocardial infarction

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

Access to Document

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