A novel bioassay platform using ferritin-based nanoprobe hydrogel

Eun Jung Lee; Keum Young Ahn; Jong Hwan Lee; Jin Seung Park; Jong Am Song; Sang Jun Sim; Eun Bong Lee; Young Joo Cha; Jeewon Lee

doi:10.1002/adma.201200728

A novel bioassay platform using ferritin-based nanoprobe hydrogel

Eun Jung Lee, Keum Young Ahn, Jong Hwan Lee, Jin Seung Park, Jong Am Song, Sang Jun Sim, Eun Bong Lee, Young Joo Cha, Jeewon Lee

Department of Chemical and Biological Engineering

Research output: Contribution to journal › Article › peer-review

32 Citations (Scopus)

Abstract

Ferritin-based nanoprobe (FBNP) hydrogel provides solutions to some of the traditional problems of bioassays. The schematic shows 3D and highly specific multiplex assays of markers for AIDS and Sjögren's syndrome using quantum-dot based reporters with different fluorescence emissions for the two syndromes. The advantages of using a hydrogel include that the stability of FBNPs is significantly enhanced within the hydrogel, FBNPs are distributed evenly throughout the hydrogel matrix, and the amount of FBNPs within the hydrogel can be well controlled.

Original language	English
Pages (from-to)	4739-4744
Number of pages	6
Journal	Advanced Materials
Volume	24
Issue number	35
DOIs	https://doi.org/10.1002/adma.201200728
Publication status	Published - 2012 Sept 11

Keywords

bioassay platforms
biomedical applications
ferritin
hydrogels
nanoprobes

ASJC Scopus subject areas

General Materials Science
Mechanics of Materials
Mechanical Engineering

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/adma.201200728

Cite this

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abstract = "Ferritin-based nanoprobe (FBNP) hydrogel provides solutions to some of the traditional problems of bioassays. The schematic shows 3D and highly specific multiplex assays of markers for AIDS and Sj{\"o}gren's syndrome using quantum-dot based reporters with different fluorescence emissions for the two syndromes. The advantages of using a hydrogel include that the stability of FBNPs is significantly enhanced within the hydrogel, FBNPs are distributed evenly throughout the hydrogel matrix, and the amount of FBNPs within the hydrogel can be well controlled.",

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AU - Lee, Eun Jung

AU - Ahn, Keum Young

AU - Lee, Jong Hwan

AU - Park, Jin Seung

AU - Song, Jong Am

AU - Sim, Sang Jun

AU - Lee, Eun Bong

AU - Cha, Young Joo

AU - Lee, Jeewon

PY - 2012/9/11

Y1 - 2012/9/11

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AB - Ferritin-based nanoprobe (FBNP) hydrogel provides solutions to some of the traditional problems of bioassays. The schematic shows 3D and highly specific multiplex assays of markers for AIDS and Sjögren's syndrome using quantum-dot based reporters with different fluorescence emissions for the two syndromes. The advantages of using a hydrogel include that the stability of FBNPs is significantly enhanced within the hydrogel, FBNPs are distributed evenly throughout the hydrogel matrix, and the amount of FBNPs within the hydrogel can be well controlled.

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KW - biomedical applications

KW - ferritin

KW - hydrogels

KW - nanoprobes

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A novel bioassay platform using ferritin-based nanoprobe hydrogel

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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