A novel polymer microneedle fabrication process for active fluidic delivery

Bernardo Cordovez, Aram J. Chung, Michael Mak, David Erickson

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)


In this article, we explore a new fabrication process for a flexible, all polymer, active fluidic delivery system, incorporating a fusion of laser micromachining and microfabrication techniques as well as rapid prototyping technology. Here, we show selective fluidic delivery from isolated microchannels through an electrochemically driven pumping reaction, demonstrate the dispensing of dose volumes up to 5.5 μl, and evaluate the device's performance in terms of its delivery speed and ejection efficiency. Finally, we move this work toward an implantable microfluidic drug delivery device by investigating the device's biocompatibility through a statistical approach that overviews the viability of bovine aortic endothelial cells on polyimide and silicon substrates.

Original languageEnglish
Pages (from-to)785-791
Number of pages7
JournalMicrofluidics and Nanofluidics
Issue number4
Publication statusPublished - 2011 Apr
Externally publishedYes


  • Electrochemistry
  • Implantable drug delivery
  • Microfluidics Polyimide
  • Rapid prototyping

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Materials Chemistry


Dive into the research topics of 'A novel polymer microneedle fabrication process for active fluidic delivery'. Together they form a unique fingerprint.

Cite this