Abstract
A peptide (F4) that inhibits angiotensin I converting enzyme (ACE) was isolated from corn gluten hydrolysate prepared with Pescalase, a serine protease from Bacillus licheniformis. The N-terminal amino acid sequence of F4 was Pro-Ser-Gly-Gln-Tyr-Tyr, having the IC50 value of 0.1 mM. The peptide (F4), at 30 mg kg-1 body weight of rat, antagonized the rat's pressor response to angiotensin I.
Original language | English |
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Pages (from-to) | 1055-1058 |
Number of pages | 4 |
Journal | Biotechnology letters |
Volume | 21 |
Issue number | 12 |
DOIs | |
Publication status | Published - 1999 |
Keywords
- Angiotensin converting enzyme
- Corn gluten
- Peptide inhibitor
- Pescalase
- Protease
ASJC Scopus subject areas
- Biotechnology
- Bioengineering
- Applied Microbiology and Biotechnology