A pneumatically controllable flexible and polymeric microfluidic valve fabricated via in situ development

Ju Yeoul Back, Ji Young Park, Jong Il Ju, Tae Soo Lee, Sang Hoon Lee

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    63 Citations (Scopus)

    Abstract

    In this paper, we have developed a pneumatically controllable polydimethylsiloxane (PDMS)-based microfluidic valve. This valve regulates 'On/Off' of flow using the thick centered membrane. To integrate the freely moving thick centered membrane, regional bonding of the PDMS layer is required. Here, we integrated such a membrane employing a water soluble mask as a regional bonding method, and the mask was washed out by flowing distilled water. The fabricated valve showed good 'On/Off' operations in accordance with the applied pneumatic pressure source. The flow rate could be regulated by the pressure applied to the inlet (regulated by changes in the height of the water column) and the compression-/vacuum-period ratio (this means the ratio of 'On' and 'Off' periods in each cycle) in the range of a few microliters per minute. For the durability test, ten valves were operated simultaneously one million times, and no failed valves were observed.

    Original languageEnglish
    Pages (from-to)1015-1020
    Number of pages6
    JournalJournal of Micromechanics and Microengineering
    Volume15
    Issue number5
    DOIs
    Publication statusPublished - 2005 May

    ASJC Scopus subject areas

    • Electronic, Optical and Magnetic Materials
    • Mechanics of Materials
    • Mechanical Engineering
    • Electrical and Electronic Engineering

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