A prospective 1-year comparative study of transaxillary total thyroidectomy regarding functional outcomes: Is it really promising?

Doh Young Lee, Saehee Lim, Sung Hoon Kang, Kyoung Ho Oh, Jae Gu Cho, Seung Kuk Baek, Jeong Soo Woo, Soon Young Kwon, Kwang Yoon Jung

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)


Background: The purpose of this study was to evaluate postoperative voice outcomes and functional parameters in total thyroidectomy via a transaxillary (TA) approach. Methods: Seventy-six patients who underwent total thyroidectomy via a TA approach (TA group) were included. A total of 204 patients who underwent conventional open total thyroidectomy (conventional group) in the same time period were analyzed as a control group. All patients underwent prospective functional evaluations before surgery and at 1 week and 1, 3, 6, and 12 months postoperatively using a comprehensive battery of functional assessments. Results: There was no conversion to conventional open thyroidectomy in the TA group. Operation time and the amount of drainage were significantly higher in the TA group than in the conventional group (p < 0.001 and p = 0.033, respectively), while vocal cord paralysis, hypoparathyroidism, and hematoma were not different among two groups (p = 0.215, 0.290, and 0.385, respectively). Regarding GRBAS, the TA group showed a more aggravated tendency postoperatively, although statistical significance was attained only at postoperative 6 months (p = 0.043). The voice handicap index abruptly increased postoperatively in the TA group, showing significant differences with the conventional group at postoperative 1 week and 1 month (p < 0.001 and p = 0.001, respectively). Fundamental frequency and maximal vocal pitch did not significantly change postoperatively in either group. The conventional group showed a more rapid decline in pain than the TA group, and paresthesias on the neck and chest were more aggravated in the TA group during the early postoperative period. The dysphagia handicap index was higher in the TA group, while cosmesis was better in the TA group at all postoperative periods. Conclusions: Although cosmetic outcome was better with the TA approach, the longer operation time, aggravated subjective voice outcomes, paresthesia, and swallowing function need to be considered in selecting the operative approach.

Original languageEnglish
Pages (from-to)1599-1606
Number of pages8
JournalSurgical Endoscopy
Issue number4
Publication statusPublished - 2016 Apr 1

Bibliographical note

Publisher Copyright:
© 2015, Springer Science+Business Media New York.


  • Conventional thyroidectomy
  • Swallowing
  • Total thyroidectomy
  • Transaxillary approach
  • Voice

ASJC Scopus subject areas

  • Surgery


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