A ratiometric fluorescent probe for detecting hypochlorite in the endoplasmic reticulum

Ji Ting Hou; Hyeong Seok Kim; Chong Duan; Myung Sun Ji; Shan Wang; Lintao Zeng; Wen Xiu Ren; Jong Seung Kim

doi:10.1039/c9cc00066f

A ratiometric fluorescent probe for detecting hypochlorite in the endoplasmic reticulum

Ji Ting Hou, Hyeong Seok Kim, Chong Duan, Myung Sun Ji, Shan Wang, Lintao Zeng, Wen Xiu Ren, Jong Seung Kim

Research output: Contribution to journal › Article › peer-review

137 Citations (Scopus)

Abstract

A colorimetric and fluorescent probe ER-ClO was presented in this work to detect cellular hypochlorite with high selectivity and sensitivity. With an organelle targeting unit, ER-ClO was successfully applied in the bio-imaging of exogenous and endogenous hypochlorite in the endoplasmic reticulum in a ratiometric manner.

Original language	English
Pages (from-to)	2533-2536
Number of pages	4
Journal	Chemical Communications
Volume	55
Issue number	17
DOIs	https://doi.org/10.1039/c9cc00066f
Publication status	Published - 2019

Bibliographical note

Funding Information:
J.-T. H. acknowledges grants from the Hubei Provincial Natural Science Foundation (2018CFB264) and the National Natural Science Foundation of China (no. 21807029); S. W. acknowledges grants from the Hubei Provincial Department of Education Science and Technology Research Projects (No. Q20182704); L. Z. acknowledges grants from the National Natural Science Foundation of China (no. 21203138) and the Natural Science Foundation of Tianjin (No. 17JCYBJC19600); J. S. K. acknowledges grants from CRI project (No. 2018R1A3B1052702).

Publisher Copyright:
© 2019 The Royal Society of Chemistry.

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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title = "A ratiometric fluorescent probe for detecting hypochlorite in the endoplasmic reticulum",

abstract = "A colorimetric and fluorescent probe ER-ClO was presented in this work to detect cellular hypochlorite with high selectivity and sensitivity. With an organelle targeting unit, ER-ClO was successfully applied in the bio-imaging of exogenous and endogenous hypochlorite in the endoplasmic reticulum in a ratiometric manner.",

author = "Hou, {Ji Ting} and Kim, {Hyeong Seok} and Chong Duan and Ji, {Myung Sun} and Shan Wang and Lintao Zeng and Ren, {Wen Xiu} and Kim, {Jong Seung}",

note = "Funding Information: J.-T. H. acknowledges grants from the Hubei Provincial Natural Science Foundation (2018CFB264) and the National Natural Science Foundation of China (no. 21807029); S. W. acknowledges grants from the Hubei Provincial Department of Education Science and Technology Research Projects (No. Q20182704); L. Z. acknowledges grants from the National Natural Science Foundation of China (no. 21203138) and the Natural Science Foundation of Tianjin (No. 17JCYBJC19600); J. S. K. acknowledges grants from CRI project (No. 2018R1A3B1052702). Publisher Copyright: {\textcopyright} 2019 The Royal Society of Chemistry.",

year = "2019",

doi = "10.1039/c9cc00066f",

language = "English",

volume = "55",

pages = "2533--2536",

journal = "Chemical Communications",

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publisher = "Royal Society of Chemistry",

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T1 - A ratiometric fluorescent probe for detecting hypochlorite in the endoplasmic reticulum

AU - Hou, Ji Ting

AU - Kim, Hyeong Seok

AU - Duan, Chong

AU - Ji, Myung Sun

AU - Wang, Shan

AU - Zeng, Lintao

AU - Ren, Wen Xiu

AU - Kim, Jong Seung

N1 - Funding Information: J.-T. H. acknowledges grants from the Hubei Provincial Natural Science Foundation (2018CFB264) and the National Natural Science Foundation of China (no. 21807029); S. W. acknowledges grants from the Hubei Provincial Department of Education Science and Technology Research Projects (No. Q20182704); L. Z. acknowledges grants from the National Natural Science Foundation of China (no. 21203138) and the Natural Science Foundation of Tianjin (No. 17JCYBJC19600); J. S. K. acknowledges grants from CRI project (No. 2018R1A3B1052702). Publisher Copyright: © 2019 The Royal Society of Chemistry.

PY - 2019

Y1 - 2019

N2 - A colorimetric and fluorescent probe ER-ClO was presented in this work to detect cellular hypochlorite with high selectivity and sensitivity. With an organelle targeting unit, ER-ClO was successfully applied in the bio-imaging of exogenous and endogenous hypochlorite in the endoplasmic reticulum in a ratiometric manner.

AB - A colorimetric and fluorescent probe ER-ClO was presented in this work to detect cellular hypochlorite with high selectivity and sensitivity. With an organelle targeting unit, ER-ClO was successfully applied in the bio-imaging of exogenous and endogenous hypochlorite in the endoplasmic reticulum in a ratiometric manner.

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DO - 10.1039/c9cc00066f

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SN - 1359-7345

VL - 55

SP - 2533

EP - 2536

JO - Chemical Communications

JF - Chemical Communications

IS - 17

ER -

A ratiometric fluorescent probe for detecting hypochlorite in the endoplasmic reticulum

Abstract

Bibliographical note

ASJC Scopus subject areas

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