A retrospective analysis of the clinical efficacies of Q-switched Alexandrite and Q-switched Nd:YAG lasers in the treatment of nevus of Ota in Korean patients

Jae Eun Choi; Joo Bong Lee; Ki Beom Park; Bang Soon Kim; Un Cheol Yeo; Chang Hun Huh; Jie Hoon Kim; Young Chul Kye

doi:10.3109/09546634.2014.930409

A retrospective analysis of the clinical efficacies of Q-switched Alexandrite and Q-switched Nd:YAG lasers in the treatment of nevus of Ota in Korean patients

Jae Eun Choi, Joo Bong Lee, Ki Beom Park, Bang Soon Kim, Un Cheol Yeo, Chang Hun Huh, Jie Hoon Kim, Young Chul Kye

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

Background: While the Q-switched Alexandrite laser (QSAL) and the Q-switched neodymium: yttrium-aluminum-garnet (QSNY) laser have been widely used in treating nevus of Ota, few studies compared them. Objective: To compare the efficacies of the QSAL and the QSNY laser in the treatment of nevus of Ota in Korean patients. Methods and materials: A retrospective multicenter study was conducted in 76 patients with nevus of Ota. Thirty-one patients were treated with a QSAL (5.5-8.0-J/cm², 4-mm spot size) and 45 patients were treated with QSNY laser (6.0-12.0-J/cm², 2-mm spot size). Treatment outcomes were categorized into five grades and the results were compared with the relevant variables taken into account using multivariate logistic regression analysis. Results: QSAL treatment was more likely to achieve a better response compared with that with QSNY laser treatment. The odds ratio of achieving an excellent response, compared with the odds ratio of having a poor response, was 12.213-times more likely when a QSAL was used than when a QSNY laser was used (p-=-0.026). Conclusion: The QSAL tends to be more efficient than the QSNY laser in the treatment of nevus of Ota in Korean patients. Further controlled, prospective comparison studies are needed.

Original language	English
Pages (from-to)	240-245
Number of pages	6
Journal	Journal of Dermatological Treatment
Volume	26
Issue number	3
DOIs	https://doi.org/10.3109/09546634.2014.930409
Publication status	Published - 2015 Jun 1
Externally published	Yes

Bibliographical note

Funding Information:
The publication of this article was financially supported by Korean Association of Dermatology. The authors report no conflicts of interest. The authors alone are responsible for the content and writing of this article.

Publisher Copyright:
© 2014 Informa UK Ltd. All rights reserved.

Keywords

Nevus of Ota
Q-switched 1064-nm neodymium: yttrium-aluminum-garnet laser
Q-switched 755-nm Alexandrite laser

ASJC Scopus subject areas

Dermatology

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10.3109/09546634.2014.930409

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@article{cb09131ba9fe46f1b8ee5f90059ddb28,

title = "A retrospective analysis of the clinical efficacies of Q-switched Alexandrite and Q-switched Nd:YAG lasers in the treatment of nevus of Ota in Korean patients",

abstract = "Background: While the Q-switched Alexandrite laser (QSAL) and the Q-switched neodymium: yttrium-aluminum-garnet (QSNY) laser have been widely used in treating nevus of Ota, few studies compared them. Objective: To compare the efficacies of the QSAL and the QSNY laser in the treatment of nevus of Ota in Korean patients. Methods and materials: A retrospective multicenter study was conducted in 76 patients with nevus of Ota. Thirty-one patients were treated with a QSAL (5.5-8.0-J/cm2, 4-mm spot size) and 45 patients were treated with QSNY laser (6.0-12.0-J/cm2, 2-mm spot size). Treatment outcomes were categorized into five grades and the results were compared with the relevant variables taken into account using multivariate logistic regression analysis. Results: QSAL treatment was more likely to achieve a better response compared with that with QSNY laser treatment. The odds ratio of achieving an excellent response, compared with the odds ratio of having a poor response, was 12.213-times more likely when a QSAL was used than when a QSNY laser was used (p-=-0.026). Conclusion: The QSAL tends to be more efficient than the QSNY laser in the treatment of nevus of Ota in Korean patients. Further controlled, prospective comparison studies are needed.",

keywords = "Nevus of Ota, Q-switched 1064-nm neodymium: yttrium-aluminum-garnet laser, Q-switched 755-nm Alexandrite laser",

author = "Choi, {Jae Eun} and Lee, {Joo Bong} and Park, {Ki Beom} and Kim, {Bang Soon} and Yeo, {Un Cheol} and Huh, {Chang Hun} and Kim, {Jie Hoon} and Kye, {Young Chul}",

note = "Funding Information: The publication of this article was financially supported by Korean Association of Dermatology. The authors report no conflicts of interest. The authors alone are responsible for the content and writing of this article. Publisher Copyright: {\textcopyright} 2014 Informa UK Ltd. All rights reserved.",

year = "2015",

month = jun,

day = "1",

doi = "10.3109/09546634.2014.930409",

language = "English",

volume = "26",

pages = "240--245",

journal = "Journal of Dermatological Treatment",

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T1 - A retrospective analysis of the clinical efficacies of Q-switched Alexandrite and Q-switched Nd:YAG lasers in the treatment of nevus of Ota in Korean patients

AU - Choi, Jae Eun

AU - Lee, Joo Bong

AU - Park, Ki Beom

AU - Kim, Bang Soon

AU - Yeo, Un Cheol

AU - Huh, Chang Hun

AU - Kim, Jie Hoon

AU - Kye, Young Chul

N1 - Funding Information: The publication of this article was financially supported by Korean Association of Dermatology. The authors report no conflicts of interest. The authors alone are responsible for the content and writing of this article. Publisher Copyright: © 2014 Informa UK Ltd. All rights reserved.

PY - 2015/6/1

Y1 - 2015/6/1

N2 - Background: While the Q-switched Alexandrite laser (QSAL) and the Q-switched neodymium: yttrium-aluminum-garnet (QSNY) laser have been widely used in treating nevus of Ota, few studies compared them. Objective: To compare the efficacies of the QSAL and the QSNY laser in the treatment of nevus of Ota in Korean patients. Methods and materials: A retrospective multicenter study was conducted in 76 patients with nevus of Ota. Thirty-one patients were treated with a QSAL (5.5-8.0-J/cm2, 4-mm spot size) and 45 patients were treated with QSNY laser (6.0-12.0-J/cm2, 2-mm spot size). Treatment outcomes were categorized into five grades and the results were compared with the relevant variables taken into account using multivariate logistic regression analysis. Results: QSAL treatment was more likely to achieve a better response compared with that with QSNY laser treatment. The odds ratio of achieving an excellent response, compared with the odds ratio of having a poor response, was 12.213-times more likely when a QSAL was used than when a QSNY laser was used (p-=-0.026). Conclusion: The QSAL tends to be more efficient than the QSNY laser in the treatment of nevus of Ota in Korean patients. Further controlled, prospective comparison studies are needed.

AB - Background: While the Q-switched Alexandrite laser (QSAL) and the Q-switched neodymium: yttrium-aluminum-garnet (QSNY) laser have been widely used in treating nevus of Ota, few studies compared them. Objective: To compare the efficacies of the QSAL and the QSNY laser in the treatment of nevus of Ota in Korean patients. Methods and materials: A retrospective multicenter study was conducted in 76 patients with nevus of Ota. Thirty-one patients were treated with a QSAL (5.5-8.0-J/cm2, 4-mm spot size) and 45 patients were treated with QSNY laser (6.0-12.0-J/cm2, 2-mm spot size). Treatment outcomes were categorized into five grades and the results were compared with the relevant variables taken into account using multivariate logistic regression analysis. Results: QSAL treatment was more likely to achieve a better response compared with that with QSNY laser treatment. The odds ratio of achieving an excellent response, compared with the odds ratio of having a poor response, was 12.213-times more likely when a QSAL was used than when a QSNY laser was used (p-=-0.026). Conclusion: The QSAL tends to be more efficient than the QSNY laser in the treatment of nevus of Ota in Korean patients. Further controlled, prospective comparison studies are needed.

KW - Nevus of Ota

KW - Q-switched 1064-nm neodymium: yttrium-aluminum-garnet laser

KW - Q-switched 755-nm Alexandrite laser

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SN - 0954-6634

VL - 26

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EP - 245

JO - Journal of Dermatological Treatment

JF - Journal of Dermatological Treatment

IS - 3

ER -

A retrospective analysis of the clinical efficacies of Q-switched Alexandrite and Q-switched Nd:YAG lasers in the treatment of nevus of Ota in Korean patients

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

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