Abstract
An effective mask-free method for fabricating high-aspect-ratio pillarlike nanostructures over a large area of a quartz surface via a simple O2 and CF4 two-step reactive ion etching (RIE) procedure is developed. The nanostructured quartz surfaces are successfully combined with the engineered viral particles derived from hepatitis B virus capsid, yielding a novel 3D assay system with attomolar sensitivity, which has great potential for use in sensitive and early detection of various disease markers.
Original language | English |
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Pages (from-to) | 2004-2009 |
Number of pages | 6 |
Journal | Advanced Functional Materials |
Volume | 20 |
Issue number | 12 |
DOIs | |
Publication status | Published - 2010 Jun 23 |
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- General Chemistry
- Condensed Matter Physics
- General Materials Science
- Electrochemistry
- Biomaterials