A three-dimensional and sensitive bioassay based on nanostructured quartz combined with viral nanoparticles

Jong Hwan Lee; Jung Suk Kim; Jin Seung Park; Wonbae Lee; Kyung Eun Lee; Sung Sik Han; Kyu Back Lee; Jeewon Lee

doi:10.1002/adfm.200902054

A three-dimensional and sensitive bioassay based on nanostructured quartz combined with viral nanoparticles

Jong Hwan Lee^*
, Jung Suk Kim
, Jin Seung Park
, Wonbae Lee
, Kyung Eun Lee
, Sung Sik Han
, Kyu Back Lee
, Jeewon Lee

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

33 Citations (Scopus)

Abstract

An effective mask-free method for fabricating high-aspect-ratio pillarlike nanostructures over a large area of a quartz surface via a simple O₂ and CF₄ two-step reactive ion etching (RIE) procedure is developed. The nanostructured quartz surfaces are successfully combined with the engineered viral particles derived from hepatitis B virus capsid, yielding a novel 3D assay system with attomolar sensitivity, which has great potential for use in sensitive and early detection of various disease markers.

Original language	English
Pages (from-to)	2004-2009
Number of pages	6
Journal	Advanced Functional Materials
Volume	20
Issue number	12
DOIs	https://doi.org/10.1002/adfm.200902054
Publication status	Published - 2010 Jun 23

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
General Chemistry
Condensed Matter Physics
General Materials Science
Electrochemistry
Biomaterials

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10.1002/adfm.200902054

Cite this

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title = "A three-dimensional and sensitive bioassay based on nanostructured quartz combined with viral nanoparticles",

abstract = "An effective mask-free method for fabricating high-aspect-ratio pillarlike nanostructures over a large area of a quartz surface via a simple O2 and CF4 two-step reactive ion etching (RIE) procedure is developed. The nanostructured quartz surfaces are successfully combined with the engineered viral particles derived from hepatitis B virus capsid, yielding a novel 3D assay system with attomolar sensitivity, which has great potential for use in sensitive and early detection of various disease markers.",

author = "Lee, \{Jong Hwan\} and Kim, \{Jung Suk\} and Park, \{Jin Seung\} and Wonbae Lee and Lee, \{Kyung Eun\} and Han, \{Sung Sik\} and Lee, \{Kyu Back\} and Jeewon Lee",

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AU - Lee, Jong Hwan

AU - Kim, Jung Suk

AU - Park, Jin Seung

AU - Lee, Wonbae

AU - Lee, Kyung Eun

AU - Han, Sung Sik

AU - Lee, Kyu Back

AU - Lee, Jeewon

PY - 2010/6/23

Y1 - 2010/6/23

N2 - An effective mask-free method for fabricating high-aspect-ratio pillarlike nanostructures over a large area of a quartz surface via a simple O2 and CF4 two-step reactive ion etching (RIE) procedure is developed. The nanostructured quartz surfaces are successfully combined with the engineered viral particles derived from hepatitis B virus capsid, yielding a novel 3D assay system with attomolar sensitivity, which has great potential for use in sensitive and early detection of various disease markers.

AB - An effective mask-free method for fabricating high-aspect-ratio pillarlike nanostructures over a large area of a quartz surface via a simple O2 and CF4 two-step reactive ion etching (RIE) procedure is developed. The nanostructured quartz surfaces are successfully combined with the engineered viral particles derived from hepatitis B virus capsid, yielding a novel 3D assay system with attomolar sensitivity, which has great potential for use in sensitive and early detection of various disease markers.

UR - https://www.scopus.com/pages/publications/77953869034

U2 - 10.1002/adfm.200902054

DO - 10.1002/adfm.200902054

M3 - Article

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VL - 20

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JO - Advanced Functional Materials

JF - Advanced Functional Materials

IS - 12

ER -

A three-dimensional and sensitive bioassay based on nanostructured quartz combined with viral nanoparticles

Abstract

UN SDGs

ASJC Scopus subject areas

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