A two-photon fluorescent probe for calcium waves in living tissue

Hwan Myung Kim, Bo Ra Kim, Jin Hee Hong, Jin Sung Park, Kyoung J. Lee, Bong Rae Cho

Research output: Contribution to journalArticlepeer-review

96 Citations (Scopus)


(Figure Presented) Intracellular messaging: The novel two-photon fluorescent probe ACa1 can visualize calcium waves in cells and living tissue for a long period of time and without any mistargeting problems (see picture). The probe is capable of monitoring the calcium waves at a depth of about 150 μm in living tissues for more than 1100 s and with no photobleaching artifacts.

Original languageEnglish
Pages (from-to)7445-7448
Number of pages4
JournalAngewandte Chemie - International Edition
Issue number39
Publication statusPublished - 2007


  • Calcium
  • Fluorescence
  • Microscopy
  • Two-photon probes

ASJC Scopus subject areas

  • Catalysis
  • General Chemistry


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