A two-photon tracer for glucose uptake

Yu Shun Tian; Hyang Yeon Lee; Chang Su Lim; Jongmin Park; Hwan Myung Kim; Yoo Na Shin; Eun Sun Kim; Hoon Jae Jeon; Seung Bum Park; Bong Rae Cho

doi:10.1002/anie.200901175

A two-photon tracer for glucose uptake

Yu Shun Tian, Hyang Yeon Lee, Chang Su Lim, Jongmin Park, Hwan Myung Kim, Yoo Na Shin, Eun Sun Kim, Hoon Jae Jeon, Seung Bum Park, Bong Rae Cho

* Honorary professors

Research output: Contribution to journal › Article › peer-review

55 Citations (Scopus)

Abstract

It takes two: Two-photon tracers (AG1, AG2) have been developed that can be excited by 780 nm fs laser pulses, can be easily loaded into cancer cells and tissues, show high photostability and negligible toxicity, and can visualize glucose uptake in living cells and tissues by two-photon microscopy (TPM). Moreover, AG2 can screen anticancer agents in cancer cells and cancer tissues at 75-150 mm depth by TPM.

Original language	English
Pages (from-to)	8027-8031
Number of pages	5
Journal	Angewandte Chemie - International Edition
Volume	48
Issue number	43
DOIs	https://doi.org/10.1002/anie.200901175
Publication status	Published - 2009 Oct 12

Keywords

Antitumor agents
Fluorescent probes
Glucose
Imaging agents
Two-photon microscopy

ASJC Scopus subject areas

Catalysis
Chemistry(all)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/anie.200901175

Cite this

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abstract = "It takes two: Two-photon tracers (AG1, AG2) have been developed that can be excited by 780 nm fs laser pulses, can be easily loaded into cancer cells and tissues, show high photostability and negligible toxicity, and can visualize glucose uptake in living cells and tissues by two-photon microscopy (TPM). Moreover, AG2 can screen anticancer agents in cancer cells and cancer tissues at 75-150 mm depth by TPM.",

keywords = "Antitumor agents, Fluorescent probes, Glucose, Imaging agents, Two-photon microscopy",

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AU - Tian, Yu Shun

AU - Lee, Hyang Yeon

AU - Lim, Chang Su

AU - Park, Jongmin

AU - Kim, Hwan Myung

AU - Shin, Yoo Na

AU - Kim, Eun Sun

AU - Jeon, Hoon Jae

AU - Park, Seung Bum

AU - Cho, Bong Rae

PY - 2009/10/12

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AB - It takes two: Two-photon tracers (AG1, AG2) have been developed that can be excited by 780 nm fs laser pulses, can be easily loaded into cancer cells and tissues, show high photostability and negligible toxicity, and can visualize glucose uptake in living cells and tissues by two-photon microscopy (TPM). Moreover, AG2 can screen anticancer agents in cancer cells and cancer tissues at 75-150 mm depth by TPM.

KW - Antitumor agents

KW - Fluorescent probes

KW - Glucose

KW - Imaging agents

KW - Two-photon microscopy

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JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 43

ER -

A two-photon tracer for glucose uptake

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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