Accuracy of model-based iterative reconstruction for CT volumetry of part-solid nodules and solid nodules in comparison with filtered back projection and hybrid iterative reconstruction at various dose settings: An anthropomorphic chest phantom study

Seung Kwan Kim; Cherry Kim; Ki Yeol Lee; Jaehyung Cha; Hyun Ju Lim; Eun Young Kang; Yu Whan Oh

doi:10.3348/kjr.2018.0893

Accuracy of model-based iterative reconstruction for CT volumetry of part-solid nodules and solid nodules in comparison with filtered back projection and hybrid iterative reconstruction at various dose settings: An anthropomorphic chest phantom study

Seung Kwan Kim, Cherry Kim, Ki Yeol Lee, Jaehyung Cha, Hyun Ju Lim, Eun Young Kang, Yu Whan Oh

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

Objective: To investigate the accuracy of model-based iterative reconstruction (MIR) for volume measurement of part-solid nodules (PSNs) and solid nodules (SNs) in comparison with filtered back projection (FBP) or hybrid iterative reconstruction (HIR) at various radiation dose settings. Materials and Methods: CT scanning was performed for eight different diameters of PSNs and SNs placed in the phantom at five radiation dose levels (120 kVp/100 mAs, 120 kVp/50 mAs, 120 kVp/20 mAs, 120 kVp/10 mAs, and 80 kVp/10 mAs). Each CT scan was reconstructed using FBP, HIR, or MIR with three different image definitions (body routine level 1 [IMR-R1], body soft tissue level 1 [IMR-ST1], and sharp plus level 1 [IMR-SP1]; Philips Healthcare). The SN and PSN volumes including each solid/ ground-glass opacity portion were measured semi-automatically, after which absolute percentage measurement errors (APEs) of the measured volumes were calculated. Image noise was calculated to assess the image quality. Results: Across all nodules and dose settings, the APEs were significantly lower in MIR than in FBP and HIR (all p < 0.01). The APEs of the smallest inner solid portion of the PSNs (3 mm) and SNs (3 mm) were the lowest when MIR (IMR-R1 and IMR-ST1) was used for reconstruction for all radiation dose settings. (IMR-R1 and IMR-ST1 at 120 kVp/100 mAs, 1.06 ± 1.36 and 8.75 ± 3.96, p < 0.001; at 120 kVp/50 mAs, 1.95 ± 1.56 and 5.61 ± 0.85, p = 0.002; at 120 kVp/20 mAs, 2.88 ± 3.68 and 5.75 ± 1.95, p = 0.001; at 120 kVp/10 mAs, 5.57 ± 6.26 and 6.32 ± 2.91, p = 0.091; at 80 kVp/10 mAs, 5.84 ± 1.96 and 6.90 ± 3.31, p = 0.632). Image noise was significantly lower in MIR than in FBP and HIR for all radiation dose settings (120 kVp/100 mAs, 3.22 ± 0.66; 120 kVp/50 mAs, 4.19 ± 1.37; 120 kVp/20 mAs, 5.49 ± 1.16; 120 kVp/10 mAs, 6.88 ± 1.91; 80 kVp/10 mAs, 12.49 ± 6.14; all p < 0.001). Conclusion: MIR was the most accurate algorithm for volume measurements of both PSNs and SNs in comparison with FBP and HIR at low-dose as well as standard-dose settings. Specifically, MIR was effective in the volume measurement of the smallest PSNs and SNs.

Original language	English
Pages (from-to)	1195-1206
Number of pages	12
Journal	Korean journal of radiology
Volume	20
Issue number	7
DOIs	https://doi.org/10.3348/kjr.2018.0893
Publication status	Published - 2019 Jul

Bibliographical note

Funding Information:
Received December 24, 2018; accepted after revision March 31, 2019. This study was supported by a National Research Foundation of Korea (NRF) grant funded by the Korean government (MSIP) (NRF-2016R1A2B4012155 and NRF-2018R1D1A1B07049989). This study was supported by a Korea University Ansan Hospital Grant (O1801231, O1700681). This study was supported by Dong-Kook Pharmaceutical. *These authors contributed equally to this work. Corresponding author: Ki Yeol Lee, MD, PhD, Department of Radiology, Ansan Hospital, Korea University College of Medicine, 123 Jeokgeum-ro, Danwon-gu, Ansan 15355, Korea. • Tel: (8231) 412-5227 • Fax: (8231) 412-4264 • E-mail: [email protected] This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https:// creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Publisher Copyright:
© 2019 The Korean Society of Radiology.

Keywords

Imaging
Lung neoplasm
Multidetector computed tomography
Phantoms
Radiation dosage

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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Kim, S. K., Kim, C., Lee, K. Y., Cha, J., Lim, H. J., Kang, E. Y., & Oh, Y. W. (2019). Accuracy of model-based iterative reconstruction for CT volumetry of part-solid nodules and solid nodules in comparison with filtered back projection and hybrid iterative reconstruction at various dose settings: An anthropomorphic chest phantom study. Korean journal of radiology, 20(7), 1195-1206. https://doi.org/10.3348/kjr.2018.0893

Accuracy of model-based iterative reconstruction for CT volumetry of part-solid nodules and solid nodules in comparison with filtered back projection and hybrid iterative reconstruction at various dose settings: An anthropomorphic chest phantom study. / Kim, Seung Kwan; Kim, Cherry; Lee, Ki Yeol et al.
In: Korean journal of radiology, Vol. 20, No. 7, 07.2019, p. 1195-1206.

Research output: Contribution to journal › Article › peer-review

Kim, SK, Kim, C, Lee, KY, Cha, J, Lim, HJ, Kang, EY & Oh, YW 2019, 'Accuracy of model-based iterative reconstruction for CT volumetry of part-solid nodules and solid nodules in comparison with filtered back projection and hybrid iterative reconstruction at various dose settings: An anthropomorphic chest phantom study', Korean journal of radiology, vol. 20, no. 7, pp. 1195-1206. https://doi.org/10.3348/kjr.2018.0893

Kim SK, Kim C, Lee KY, Cha J, Lim HJ, Kang EY et al. Accuracy of model-based iterative reconstruction for CT volumetry of part-solid nodules and solid nodules in comparison with filtered back projection and hybrid iterative reconstruction at various dose settings: An anthropomorphic chest phantom study. Korean journal of radiology. 2019 Jul;20(7):1195-1206. doi: 10.3348/kjr.2018.0893

Kim, Seung Kwan ; Kim, Cherry ; Lee, Ki Yeol et al. / Accuracy of model-based iterative reconstruction for CT volumetry of part-solid nodules and solid nodules in comparison with filtered back projection and hybrid iterative reconstruction at various dose settings : An anthropomorphic chest phantom study. In: Korean journal of radiology. 2019 ; Vol. 20, No. 7. pp. 1195-1206.

@article{c3b5ed1768d44ac5a4d2457a8058c27a,

title = "Accuracy of model-based iterative reconstruction for CT volumetry of part-solid nodules and solid nodules in comparison with filtered back projection and hybrid iterative reconstruction at various dose settings: An anthropomorphic chest phantom study",

abstract = "Objective: To investigate the accuracy of model-based iterative reconstruction (MIR) for volume measurement of part-solid nodules (PSNs) and solid nodules (SNs) in comparison with filtered back projection (FBP) or hybrid iterative reconstruction (HIR) at various radiation dose settings. Materials and Methods: CT scanning was performed for eight different diameters of PSNs and SNs placed in the phantom at five radiation dose levels (120 kVp/100 mAs, 120 kVp/50 mAs, 120 kVp/20 mAs, 120 kVp/10 mAs, and 80 kVp/10 mAs). Each CT scan was reconstructed using FBP, HIR, or MIR with three different image definitions (body routine level 1 [IMR-R1], body soft tissue level 1 [IMR-ST1], and sharp plus level 1 [IMR-SP1]; Philips Healthcare). The SN and PSN volumes including each solid/ ground-glass opacity portion were measured semi-automatically, after which absolute percentage measurement errors (APEs) of the measured volumes were calculated. Image noise was calculated to assess the image quality. Results: Across all nodules and dose settings, the APEs were significantly lower in MIR than in FBP and HIR (all p < 0.01). The APEs of the smallest inner solid portion of the PSNs (3 mm) and SNs (3 mm) were the lowest when MIR (IMR-R1 and IMR-ST1) was used for reconstruction for all radiation dose settings. (IMR-R1 and IMR-ST1 at 120 kVp/100 mAs, 1.06 ± 1.36 and 8.75 ± 3.96, p < 0.001; at 120 kVp/50 mAs, 1.95 ± 1.56 and 5.61 ± 0.85, p = 0.002; at 120 kVp/20 mAs, 2.88 ± 3.68 and 5.75 ± 1.95, p = 0.001; at 120 kVp/10 mAs, 5.57 ± 6.26 and 6.32 ± 2.91, p = 0.091; at 80 kVp/10 mAs, 5.84 ± 1.96 and 6.90 ± 3.31, p = 0.632). Image noise was significantly lower in MIR than in FBP and HIR for all radiation dose settings (120 kVp/100 mAs, 3.22 ± 0.66; 120 kVp/50 mAs, 4.19 ± 1.37; 120 kVp/20 mAs, 5.49 ± 1.16; 120 kVp/10 mAs, 6.88 ± 1.91; 80 kVp/10 mAs, 12.49 ± 6.14; all p < 0.001). Conclusion: MIR was the most accurate algorithm for volume measurements of both PSNs and SNs in comparison with FBP and HIR at low-dose as well as standard-dose settings. Specifically, MIR was effective in the volume measurement of the smallest PSNs and SNs.",

keywords = "Imaging, Lung neoplasm, Multidetector computed tomography, Phantoms, Radiation dosage",

author = "Kim, {Seung Kwan} and Cherry Kim and Lee, {Ki Yeol} and Jaehyung Cha and Lim, {Hyun Ju} and Kang, {Eun Young} and Oh, {Yu Whan}",

note = "Funding Information: Received December 24, 2018; accepted after revision March 31, 2019. This study was supported by a National Research Foundation of Korea (NRF) grant funded by the Korean government (MSIP) (NRF-2016R1A2B4012155 and NRF-2018R1D1A1B07049989). This study was supported by a Korea University Ansan Hospital Grant (O1801231, O1700681). This study was supported by Dong-Kook Pharmaceutical. *These authors contributed equally to this work. Corresponding author: Ki Yeol Lee, MD, PhD, Department of Radiology, Ansan Hospital, Korea University College of Medicine, 123 Jeokgeum-ro, Danwon-gu, Ansan 15355, Korea. • Tel: (8231) 412-5227 • Fax: (8231) 412-4264 • E-mail: [email protected] This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https:// creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Publisher Copyright: {\textcopyright} 2019 The Korean Society of Radiology.",

year = "2019",

month = jul,

doi = "10.3348/kjr.2018.0893",

language = "English",

volume = "20",

pages = "1195--1206",

journal = "Korean journal of radiology",

issn = "1229-6929",

publisher = "Korean Radiological Society",

number = "7",

}

TY - JOUR

T1 - Accuracy of model-based iterative reconstruction for CT volumetry of part-solid nodules and solid nodules in comparison with filtered back projection and hybrid iterative reconstruction at various dose settings

T2 - An anthropomorphic chest phantom study

AU - Kim, Seung Kwan

AU - Kim, Cherry

AU - Lee, Ki Yeol

AU - Cha, Jaehyung

AU - Lim, Hyun Ju

AU - Kang, Eun Young

AU - Oh, Yu Whan

N1 - Funding Information: Received December 24, 2018; accepted after revision March 31, 2019. This study was supported by a National Research Foundation of Korea (NRF) grant funded by the Korean government (MSIP) (NRF-2016R1A2B4012155 and NRF-2018R1D1A1B07049989). This study was supported by a Korea University Ansan Hospital Grant (O1801231, O1700681). This study was supported by Dong-Kook Pharmaceutical. *These authors contributed equally to this work. Corresponding author: Ki Yeol Lee, MD, PhD, Department of Radiology, Ansan Hospital, Korea University College of Medicine, 123 Jeokgeum-ro, Danwon-gu, Ansan 15355, Korea. • Tel: (8231) 412-5227 • Fax: (8231) 412-4264 • E-mail: [email protected] This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https:// creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Publisher Copyright: © 2019 The Korean Society of Radiology.

PY - 2019/7

Y1 - 2019/7

N2 - Objective: To investigate the accuracy of model-based iterative reconstruction (MIR) for volume measurement of part-solid nodules (PSNs) and solid nodules (SNs) in comparison with filtered back projection (FBP) or hybrid iterative reconstruction (HIR) at various radiation dose settings. Materials and Methods: CT scanning was performed for eight different diameters of PSNs and SNs placed in the phantom at five radiation dose levels (120 kVp/100 mAs, 120 kVp/50 mAs, 120 kVp/20 mAs, 120 kVp/10 mAs, and 80 kVp/10 mAs). Each CT scan was reconstructed using FBP, HIR, or MIR with three different image definitions (body routine level 1 [IMR-R1], body soft tissue level 1 [IMR-ST1], and sharp plus level 1 [IMR-SP1]; Philips Healthcare). The SN and PSN volumes including each solid/ ground-glass opacity portion were measured semi-automatically, after which absolute percentage measurement errors (APEs) of the measured volumes were calculated. Image noise was calculated to assess the image quality. Results: Across all nodules and dose settings, the APEs were significantly lower in MIR than in FBP and HIR (all p < 0.01). The APEs of the smallest inner solid portion of the PSNs (3 mm) and SNs (3 mm) were the lowest when MIR (IMR-R1 and IMR-ST1) was used for reconstruction for all radiation dose settings. (IMR-R1 and IMR-ST1 at 120 kVp/100 mAs, 1.06 ± 1.36 and 8.75 ± 3.96, p < 0.001; at 120 kVp/50 mAs, 1.95 ± 1.56 and 5.61 ± 0.85, p = 0.002; at 120 kVp/20 mAs, 2.88 ± 3.68 and 5.75 ± 1.95, p = 0.001; at 120 kVp/10 mAs, 5.57 ± 6.26 and 6.32 ± 2.91, p = 0.091; at 80 kVp/10 mAs, 5.84 ± 1.96 and 6.90 ± 3.31, p = 0.632). Image noise was significantly lower in MIR than in FBP and HIR for all radiation dose settings (120 kVp/100 mAs, 3.22 ± 0.66; 120 kVp/50 mAs, 4.19 ± 1.37; 120 kVp/20 mAs, 5.49 ± 1.16; 120 kVp/10 mAs, 6.88 ± 1.91; 80 kVp/10 mAs, 12.49 ± 6.14; all p < 0.001). Conclusion: MIR was the most accurate algorithm for volume measurements of both PSNs and SNs in comparison with FBP and HIR at low-dose as well as standard-dose settings. Specifically, MIR was effective in the volume measurement of the smallest PSNs and SNs.

AB - Objective: To investigate the accuracy of model-based iterative reconstruction (MIR) for volume measurement of part-solid nodules (PSNs) and solid nodules (SNs) in comparison with filtered back projection (FBP) or hybrid iterative reconstruction (HIR) at various radiation dose settings. Materials and Methods: CT scanning was performed for eight different diameters of PSNs and SNs placed in the phantom at five radiation dose levels (120 kVp/100 mAs, 120 kVp/50 mAs, 120 kVp/20 mAs, 120 kVp/10 mAs, and 80 kVp/10 mAs). Each CT scan was reconstructed using FBP, HIR, or MIR with three different image definitions (body routine level 1 [IMR-R1], body soft tissue level 1 [IMR-ST1], and sharp plus level 1 [IMR-SP1]; Philips Healthcare). The SN and PSN volumes including each solid/ ground-glass opacity portion were measured semi-automatically, after which absolute percentage measurement errors (APEs) of the measured volumes were calculated. Image noise was calculated to assess the image quality. Results: Across all nodules and dose settings, the APEs were significantly lower in MIR than in FBP and HIR (all p < 0.01). The APEs of the smallest inner solid portion of the PSNs (3 mm) and SNs (3 mm) were the lowest when MIR (IMR-R1 and IMR-ST1) was used for reconstruction for all radiation dose settings. (IMR-R1 and IMR-ST1 at 120 kVp/100 mAs, 1.06 ± 1.36 and 8.75 ± 3.96, p < 0.001; at 120 kVp/50 mAs, 1.95 ± 1.56 and 5.61 ± 0.85, p = 0.002; at 120 kVp/20 mAs, 2.88 ± 3.68 and 5.75 ± 1.95, p = 0.001; at 120 kVp/10 mAs, 5.57 ± 6.26 and 6.32 ± 2.91, p = 0.091; at 80 kVp/10 mAs, 5.84 ± 1.96 and 6.90 ± 3.31, p = 0.632). Image noise was significantly lower in MIR than in FBP and HIR for all radiation dose settings (120 kVp/100 mAs, 3.22 ± 0.66; 120 kVp/50 mAs, 4.19 ± 1.37; 120 kVp/20 mAs, 5.49 ± 1.16; 120 kVp/10 mAs, 6.88 ± 1.91; 80 kVp/10 mAs, 12.49 ± 6.14; all p < 0.001). Conclusion: MIR was the most accurate algorithm for volume measurements of both PSNs and SNs in comparison with FBP and HIR at low-dose as well as standard-dose settings. Specifically, MIR was effective in the volume measurement of the smallest PSNs and SNs.

KW - Imaging

KW - Lung neoplasm

KW - Multidetector computed tomography

KW - Phantoms

KW - Radiation dosage

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DO - 10.3348/kjr.2018.0893

M3 - Article

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AN - SCOPUS:85069268662

SN - 1229-6929

VL - 20

SP - 1195

EP - 1206

JO - Korean journal of radiology

JF - Korean journal of radiology

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ER -

Accuracy of model-based iterative reconstruction for CT volumetry of part-solid nodules and solid nodules in comparison with filtered back projection and hybrid iterative reconstruction at various dose settings: An anthropomorphic chest phantom study

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Bibliographical note

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