Acid-triggered release of doxorubicin from a hydrazone-linked Gd3+-texaphyrin conjugate

Min Hee Lee, Eun Joong Kim, Hyunseung Lee, Sun Young Park, Kwan Soo Hong, Jong Seung Kim, Jonathan L. Sessler

Research output: Contribution to journalArticlepeer-review

15 Citations (Scopus)

Abstract

The hydrazone-based Gd3+-texaphyrin doxorubicin conjugate 1, releases active doxorubicin at acidic pH values, allowing its components to be followed by two complementary imaging methods, namely Off-On fluorescence enhancement and MR imaging. It thus acts as a promising theranostic agent.

Original languageEnglish
Pages (from-to)10551-10554
Number of pages4
JournalChemical Communications
Volume52
Issue number69
DOIs
Publication statusPublished - 2016

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • General Chemistry
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Fingerprint

Dive into the research topics of 'Acid-triggered release of doxorubicin from a hydrazone-linked Gd3+-texaphyrin conjugate'. Together they form a unique fingerprint.

Cite this