Ameliorating effects of a nopal (Opuntia ficus-indica) complex on blood glucose in db/db mice

Yong Suk Son; Jin A. Yoon; Sung Joon Lee; Han Kyeom Kim

doi:10.1007/s10068-011-0035-4

Ameliorating effects of a nopal (Opuntia ficus-indica) complex on blood glucose in db/db mice

Yong Suk Son, Jin A. Yoon, Sung Joon Lee, Han Kyeom Kim

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

This study investigated the effects of a nopal (Opuntia ficus-indica) complex (OF) on blood glucose metabolism in db/db mice for 4 weeks. Food and water intake significantly decreased in OF-treated mice compared to controls (p<0.05). In addition, blood glucose and plasma insulin levels were significantly reduced in the OF-treated group compared to the controls (p<0.05). Histopathological analysis showed that the morphology of pancreatic islets was improved in the OF-treated db/db mice. Immunohistochemistry of the pancreatic islets showed that insulin production and the number of β-cells apparently increased.

Original language	English
Pages (from-to)	255-259
Number of pages	5
Journal	Food Science and Biotechnology
Volume	20
Issue number	1
DOIs	https://doi.org/10.1007/s10068-011-0035-4
Publication status	Published - 2011 Feb

Keywords

Hypoglycemic
Insulin
Opuntia ficus-indica
Pancreatic islet
db/db mice

ASJC Scopus subject areas

Biotechnology
Food Science
Applied Microbiology and Biotechnology

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10.1007/s10068-011-0035-4

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abstract = "This study investigated the effects of a nopal (Opuntia ficus-indica) complex (OF) on blood glucose metabolism in db/db mice for 4 weeks. Food and water intake significantly decreased in OF-treated mice compared to controls (p<0.05). In addition, blood glucose and plasma insulin levels were significantly reduced in the OF-treated group compared to the controls (p<0.05). Histopathological analysis showed that the morphology of pancreatic islets was improved in the OF-treated db/db mice. Immunohistochemistry of the pancreatic islets showed that insulin production and the number of β-cells apparently increased.",

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AU - Yoon, Jin A.

AU - Lee, Sung Joon

AU - Kim, Han Kyeom

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KW - Insulin

KW - Opuntia ficus-indica

KW - Pancreatic islet

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Ameliorating effects of a nopal (Opuntia ficus-indica) complex on blood glucose in db/db mice

Abstract

Keywords

ASJC Scopus subject areas

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