TY - JOUR
T1 - An Efficient Switching-Off of Coherent Anti-Stokes Raman Scattering via Double Stimulated Raman Scattering Processes of Heteromolecular Vibrational Modes
AU - Lim, Sohee
AU - Choi, Dae Sik
AU - Rhee, Hanju
AU - Cho, Minhaeng
N1 - Funding Information:
This work was supported by the Institute for Basic Science (IBS-R023-D1) to M.C. and by the Korea Basic Science Institute (KBSI) D39617 to H.R. All of the SRL and CARS measurements were performed using the femtosecond Multi-Dimensional Laser Spectroscopic System (FMLS) at the KBSI.
Publisher Copyright:
Copyright © 2020 American Chemical Society.
PY - 2020/4/30
Y1 - 2020/4/30
N2 - Recently, we introduced a new switching-off technique applicable to subdiffraction-limited coherent Raman imaging, where a coherent anti-Stokes Raman scattering (CARS) signal can be selectively suppressed via competitive stimulated Raman scattering (SRS) processes between vibrational modes of a single molecular species. Here, we show that such a three-beam CARS suppression can be made via double SRS processes between vibrational modes of heteromolecular species, a mixture of paraffin oil and benzene. We achieve more than 80% suppression of the pump-Stokes-beam CARS signal for the ring-breathing mode (target mode) of benzene when the C-H stretching mode (acceptor mode) of paraffin oil is used to deplete the pump photons via the pump-depletion-beam SRS process. The freedom in the choice of acceptor mode for depletion, which could be a critical advantage of the present switching-off scheme, can be of use for overcoming current challenges of depletion-based super-resolution coherent Raman imaging of biomolecules.
AB - Recently, we introduced a new switching-off technique applicable to subdiffraction-limited coherent Raman imaging, where a coherent anti-Stokes Raman scattering (CARS) signal can be selectively suppressed via competitive stimulated Raman scattering (SRS) processes between vibrational modes of a single molecular species. Here, we show that such a three-beam CARS suppression can be made via double SRS processes between vibrational modes of heteromolecular species, a mixture of paraffin oil and benzene. We achieve more than 80% suppression of the pump-Stokes-beam CARS signal for the ring-breathing mode (target mode) of benzene when the C-H stretching mode (acceptor mode) of paraffin oil is used to deplete the pump photons via the pump-depletion-beam SRS process. The freedom in the choice of acceptor mode for depletion, which could be a critical advantage of the present switching-off scheme, can be of use for overcoming current challenges of depletion-based super-resolution coherent Raman imaging of biomolecules.
UR - http://www.scopus.com/inward/record.url?scp=85084185970&partnerID=8YFLogxK
U2 - 10.1021/acs.jpcb.0c03080
DO - 10.1021/acs.jpcb.0c03080
M3 - Article
C2 - 32271574
AN - SCOPUS:85084185970
SN - 1520-6106
VL - 124
SP - 3583
EP - 3590
JO - Journal of Physical Chemistry B
JF - Journal of Physical Chemistry B
IS - 17
ER -