An ultra-sensitive colorimetric detection of tetracyclines using the shortest aptamer with highly enhanced affinity

Young Seop Kwon; Nurul Hanun Ahmad Raston; Man Bock Gu

doi:10.1039/c3cc47108j

An ultra-sensitive colorimetric detection of tetracyclines using the shortest aptamer with highly enhanced affinity

Young Seop Kwon, Nurul Hanun Ahmad Raston, Man Bock Gu

Department of Biotechnology

Research output: Contribution to journal › Article › peer-review

87 Citations (Scopus)

Abstract

A shortened 8-mer ssDNA aptamer was successfully truncated for four different tetracyclines with high affinity. The ultrasensitive colorimetric detection of oxytetracycline using this shortened aptamer was possible, which was about 500-fold enhanced compared to that obtained using the original 76-mer aptamer.

Original language	English
Pages (from-to)	40-42
Number of pages	3
Journal	Chemical Communications
Volume	50
Issue number	1
DOIs	https://doi.org/10.1039/c3cc47108j
Publication status	Published - 2014 Nov 26

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Chemistry(all)
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

Access to Document

10.1039/c3cc47108j

Cite this

@article{abd2ae5229054917a5bd2914d04615d9,

title = "An ultra-sensitive colorimetric detection of tetracyclines using the shortest aptamer with highly enhanced affinity",

abstract = "A shortened 8-mer ssDNA aptamer was successfully truncated for four different tetracyclines with high affinity. The ultrasensitive colorimetric detection of oxytetracycline using this shortened aptamer was possible, which was about 500-fold enhanced compared to that obtained using the original 76-mer aptamer.",

author = "Kwon, {Young Seop} and {Ahmad Raston}, {Nurul Hanun} and Gu, {Man Bock}",

year = "2014",

month = nov,

day = "26",

doi = "10.1039/c3cc47108j",

language = "English",

volume = "50",

pages = "40--42",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "1",

}

TY - JOUR

T1 - An ultra-sensitive colorimetric detection of tetracyclines using the shortest aptamer with highly enhanced affinity

AU - Kwon, Young Seop

AU - Ahmad Raston, Nurul Hanun

AU - Gu, Man Bock

PY - 2014/11/26

Y1 - 2014/11/26

N2 - A shortened 8-mer ssDNA aptamer was successfully truncated for four different tetracyclines with high affinity. The ultrasensitive colorimetric detection of oxytetracycline using this shortened aptamer was possible, which was about 500-fold enhanced compared to that obtained using the original 76-mer aptamer.

AB - A shortened 8-mer ssDNA aptamer was successfully truncated for four different tetracyclines with high affinity. The ultrasensitive colorimetric detection of oxytetracycline using this shortened aptamer was possible, which was about 500-fold enhanced compared to that obtained using the original 76-mer aptamer.

UR - http://www.scopus.com/inward/record.url?scp=84888600562&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84888600562&partnerID=8YFLogxK

U2 - 10.1039/c3cc47108j

DO - 10.1039/c3cc47108j

M3 - Article

C2 - 24185440

AN - SCOPUS:84888600562

SN - 1359-7345

VL - 50

SP - 40

EP - 42

JO - Chemical Communications

JF - Chemical Communications

IS - 1

ER -

An ultra-sensitive colorimetric detection of tetracyclines using the shortest aptamer with highly enhanced affinity

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this