An ultra-sensitive colorimetric detection of tetracyclines using the shortest aptamer with highly enhanced affinity

Young Seop Kwon; Nurul Hanun Ahmad Raston; Man Bock Gu

doi:10.1039/c3cc47108j

An ultra-sensitive colorimetric detection of tetracyclines using the shortest aptamer with highly enhanced affinity

Young Seop Kwon, Nurul Hanun Ahmad Raston, Man Bock Gu

Department of Biotechnology

Research output: Contribution to journal › Article › peer-review

78 Citations (Scopus)

Abstract

A shortened 8-mer ssDNA aptamer was successfully truncated for four different tetracyclines with high affinity. The ultrasensitive colorimetric detection of oxytetracycline using this shortened aptamer was possible, which was about 500-fold enhanced compared to that obtained using the original 76-mer aptamer.

Original language	English
Pages (from-to)	40-42
Number of pages	3
Journal	Chemical Communications
Volume	50
Issue number	1
DOIs	https://doi.org/10.1039/c3cc47108j
Publication status	Published - 2014 Nov 26

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Chemistry(all)
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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abstract = "A shortened 8-mer ssDNA aptamer was successfully truncated for four different tetracyclines with high affinity. The ultrasensitive colorimetric detection of oxytetracycline using this shortened aptamer was possible, which was about 500-fold enhanced compared to that obtained using the original 76-mer aptamer.",

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AB - A shortened 8-mer ssDNA aptamer was successfully truncated for four different tetracyclines with high affinity. The ultrasensitive colorimetric detection of oxytetracycline using this shortened aptamer was possible, which was about 500-fold enhanced compared to that obtained using the original 76-mer aptamer.

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An ultra-sensitive colorimetric detection of tetracyclines using the shortest aptamer with highly enhanced affinity

Abstract

ASJC Scopus subject areas

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