An ultrasensitive and incubation-free electrochemical immunosensor using a gold-nanocatalyst label mediating outer-sphere-reaction-philic and inner-sphere-reaction-philic species

Chiew San Fang; Kyung Hwan Oh; Aram Oh; Kwangyeol Lee; Seonhwa Park; Sinyoung Kim; Jin Kyoon Park; Haesik Yang

doi:10.1039/c6cc00353b

An ultrasensitive and incubation-free electrochemical immunosensor using a gold-nanocatalyst label mediating outer-sphere-reaction-philic and inner-sphere-reaction-philic species

Chiew San Fang, Kyung Hwan Oh, Aram Oh, Kwangyeol Lee, Seonhwa Park, Sinyoung Kim, Jin Kyoon Park, Haesik Yang

Research output: Contribution to journal › Article › peer-review

28 Citations (Scopus)

Abstract

This communication reports a new nanocatalytic scheme based on the facts that the redox reaction between a highly outer-sphere-reaction-philic (OSR-philic) species and a highly inner-sphere-reaction-philic (ISR-philic) species is slow and that an OSR- and ISR-philic Au-nanocatalyst label can mediate the two different types of redox species. This scheme allows highly sensitive and incubation free detection of creatine kinase-MB.

Original language	English
Pages (from-to)	5884-5887
Number of pages	4
Journal	Chemical Communications
Volume	52
Issue number	34
DOIs	https://doi.org/10.1039/c6cc00353b
Publication status	Published - 2016 Apr 30

Bibliographical note

Publisher Copyright:
© The Royal Society of Chemistry 2016.

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/c6cc00353b

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An ultrasensitive and incubation-free electrochemical immunosensor using a gold-nanocatalyst label mediating outer-sphere-reaction-philic and inner-sphere-reaction-philic species. / Fang, Chiew San; Oh, Kyung Hwan; Oh, Aram et al.
In: Chemical Communications, Vol. 52, No. 34, 30.04.2016, p. 5884-5887.

Research output: Contribution to journal › Article › peer-review

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abstract = "This communication reports a new nanocatalytic scheme based on the facts that the redox reaction between a highly outer-sphere-reaction-philic (OSR-philic) species and a highly inner-sphere-reaction-philic (ISR-philic) species is slow and that an OSR- and ISR-philic Au-nanocatalyst label can mediate the two different types of redox species. This scheme allows highly sensitive and incubation free detection of creatine kinase-MB.",

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AU - Oh, Aram

AU - Lee, Kwangyeol

AU - Park, Seonhwa

AU - Kim, Sinyoung

AU - Park, Jin Kyoon

AU - Yang, Haesik

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AB - This communication reports a new nanocatalytic scheme based on the facts that the redox reaction between a highly outer-sphere-reaction-philic (OSR-philic) species and a highly inner-sphere-reaction-philic (ISR-philic) species is slow and that an OSR- and ISR-philic Au-nanocatalyst label can mediate the two different types of redox species. This scheme allows highly sensitive and incubation free detection of creatine kinase-MB.

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An ultrasensitive and incubation-free electrochemical immunosensor using a gold-nanocatalyst label mediating outer-sphere-reaction-philic and inner-sphere-reaction-philic species

Abstract

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