Analysis of age-related prevalence and risk factors of chronic rhinosinusitis with asthma

Junhu Tai, Yujin Jeong, Kijeong Lee, Jaehyung Park, Munsoo Han, Tae Hoon Kim

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


Objective: To determine age-related risk factors for chronic rhinosinusitis (CRS) with asthma. Methods: Data were obtained from a national survey of non-hospitalized civilians conducted by the Korean Center for Disease Control and Prevention. CRS diagnosis was based on the guidelines of the European Position Paper on Rhinosinusitis and Nasal Polyps 2020. Asthma was judged based on whether the patient had been diagnosed with asthma in the past. Of the 45,811 survey participants, 26,335 were included in the cross-sectional study. Participants included in the study were divided into the control, CRS, and CRS with asthma groups. Age-related risk factors were analyzed in patients aged < 60 or > 60 years. Univariate logistic analyses were performed to evaluate the relationship between groups. Risk factors included age, sex, household income, residence, education level, occupation, and body mass index (BMI). Results: Education level (Odds Ratio [OR]: 0.342, P =.0003), BMI (OR: 1.09, P =.0082), and total IgE (TIgE) levels (OR: 5.582, P =.003) were significantly different between the control and the CRS with asthma group. Education level (OR: 0.478, P =.0016) and TIgE levels (OR: 4, P =.0218) were significantly different between the CRS and CRS with asthma groups under 60 years of age. BMI (OR: 1.087, P =.0443; OR: 1.104, P =.0224) showed a significant difference between all three groups with age > 60 years. Conclusion: Progression to CRS with asthma is influenced by education level, occupation, and TIgE levels in patients under 60 years of age. BMI was the only influencing factor associated with the progression to CRS with asthma in those aged > 60 years.

Original languageEnglish
Pages (from-to)55-61
Number of pages7
JournalEar, Nose and Throat Journal
Issue number1
Publication statusPublished - 2024 Jan

Bibliographical note

Publisher Copyright:
© The Author(s) 2022.


  • age
  • asthma
  • big data
  • chronic rhinosinusitis
  • prevalence
  • risk factor
  • united airway

ASJC Scopus subject areas

  • Otorhinolaryngology


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