Antibiotic Scars Left on the Gut Microbiota from the Stringent Response

Hyojeong Yi, Heenam Stanley Kim

Research output: Contribution to journalShort surveypeer-review

6 Citations (Scopus)


Current research is primarily focused on compositional shifts and alterations in the metabolic status of the gut microbiota to elucidate the damage caused by antibiotics. However, the impact of the stringent response, which is governed by a global gene regulatory system conserved in most gut bacteria, should not be overlooked.

Original languageEnglish
Pages (from-to)735-737
Number of pages3
JournalTrends in Microbiology
Issue number9
Publication statusPublished - 2018 Sept

Bibliographical note

Funding Information:
This work was supported by grants 2018M3A9F3055921 , 2018R1A2B2006456 , and 2015M3C9A4053393 from the National Research Foundation (NRF) of the Republic of Korea . Additional support was provided by grant 2016R1A6A3A11935950 for research fellows from the NRF of the Republic of Korea to HY.

Publisher Copyright:
© 2018 Elsevier Ltd


  • (p)ppGpp
  • antibiotic persistence
  • antibiotic tolerance
  • gut microbiota
  • stringent response

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)
  • Virology
  • Infectious Diseases


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