Antihistamine pretreatment to reduce incidence of withdrawal movement after rocuronium injection

Ho Jun Lee; Sung Jin Han; Heezoo Kim; Il Ok Lee; Myoung Hoon Kong; Nan Suk Kim; Sang Ho Lim; Mi Kyoung Lee

doi:10.3346/jkms.2009.24.5.879

Antihistamine pretreatment to reduce incidence of withdrawal movement after rocuronium injection

Ho Jun Lee
, Sung Jin Han
, Heezoo Kim
, Il Ok Lee
, Myoung Hoon Kong
, Nan Suk Kim
, Sang Ho Lim
, Mi Kyoung Lee^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

Abstract

The purpose of this study was to determine the effectiveness of antihistamine therapy for withdrawal movements caused by rocuronium injection. One hundred seventy one ASA I-II adults undergoing elective surgery were randomly assigned to one of two groups. Patients in the control group (Group C) were premedicated with 2 mL normal saline, and those in the antihistamine group (Group A) were pre-medicated with 2 mL (45.5 mg) pheniramine maleate. After the administration of thiopental sodium 5 mg/kg, rocuronium 0.6 mg/kg was injected. Withdrawal movements were assessed using a four-grade scale. The administration of antihistamine reveals lower grade of withdrawal movement after rocuronium injection.

Original language	English
Pages (from-to)	879-882
Number of pages	4
Journal	Journal of Korean medical science
Volume	24
Issue number	5
DOIs	https://doi.org/10.3346/jkms.2009.24.5.879
Publication status	Published - 2009 Oct
Externally published	Yes

Keywords

Antihistamine
Pain
Rocuronium

ASJC Scopus subject areas

General Medicine

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10.3346/jkms.2009.24.5.879

Cite this

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title = "Antihistamine pretreatment to reduce incidence of withdrawal movement after rocuronium injection",

abstract = "The purpose of this study was to determine the effectiveness of antihistamine therapy for withdrawal movements caused by rocuronium injection. One hundred seventy one ASA I-II adults undergoing elective surgery were randomly assigned to one of two groups. Patients in the control group (Group C) were premedicated with 2 mL normal saline, and those in the antihistamine group (Group A) were pre-medicated with 2 mL (45.5 mg) pheniramine maleate. After the administration of thiopental sodium 5 mg/kg, rocuronium 0.6 mg/kg was injected. Withdrawal movements were assessed using a four-grade scale. The administration of antihistamine reveals lower grade of withdrawal movement after rocuronium injection.",

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author = "Lee, \{Ho Jun\} and Han, \{Sung Jin\} and Heezoo Kim and Lee, \{Il Ok\} and Kong, \{Myoung Hoon\} and Kim, \{Nan Suk\} and Lim, \{Sang Ho\} and Lee, \{Mi Kyoung\}",

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language = "English",

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T1 - Antihistamine pretreatment to reduce incidence of withdrawal movement after rocuronium injection

AU - Lee, Ho Jun

AU - Han, Sung Jin

AU - Kim, Heezoo

AU - Lee, Il Ok

AU - Kong, Myoung Hoon

AU - Kim, Nan Suk

AU - Lim, Sang Ho

AU - Lee, Mi Kyoung

PY - 2009/10

Y1 - 2009/10

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AB - The purpose of this study was to determine the effectiveness of antihistamine therapy for withdrawal movements caused by rocuronium injection. One hundred seventy one ASA I-II adults undergoing elective surgery were randomly assigned to one of two groups. Patients in the control group (Group C) were premedicated with 2 mL normal saline, and those in the antihistamine group (Group A) were pre-medicated with 2 mL (45.5 mg) pheniramine maleate. After the administration of thiopental sodium 5 mg/kg, rocuronium 0.6 mg/kg was injected. Withdrawal movements were assessed using a four-grade scale. The administration of antihistamine reveals lower grade of withdrawal movement after rocuronium injection.

KW - Antihistamine

KW - Pain

KW - Rocuronium

UR - https://www.scopus.com/pages/publications/75349102645

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DO - 10.3346/jkms.2009.24.5.879

M3 - Article

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AN - SCOPUS:75349102645

SN - 1011-8934

VL - 24

SP - 879

EP - 882

JO - Journal of Korean medical science

JF - Journal of Korean medical science

IS - 5

ER -

Antihistamine pretreatment to reduce incidence of withdrawal movement after rocuronium injection

Abstract

Keywords

ASJC Scopus subject areas

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