Antimicrobial susceptibility of uropathogens causing acute uncomplicated cystitis in female outpatients in South Korea: A multicentre study in 2002

Seung Ju Lee; Sang Don Lee; In Rae Cho; Bong Suck Sim; Jeong Gu Lee; Chul Sung Kim; Min Eui Kim; Yong Hyun Cho; Young Nam Woo

doi:10.1016/j.ijantimicag.2004.02.012

Antimicrobial susceptibility of uropathogens causing acute uncomplicated cystitis in female outpatients in South Korea: A multicentre study in 2002

Seung Ju Lee, Sang Don Lee, In Rae Cho, Bong Suck Sim, Jeong Gu Lee, Chul Sung Kim, Min Eui Kim, Yong Hyun Cho, Young Nam Woo

Research output: Contribution to journal › Article › peer-review

25 Citations (Scopus)

Abstract

The objective of this study was to obtain data on the susceptibility of pathogens responsible for acute uncomplicated cystitis in South Korea to currently used antimicrobial agents. A total of 239 isolates were obtained from female outpatients with acute uncomplicated cystitis. The most prevalent causative organism was Escherichia coli (79.9%), followed by coagulase-negative staphylococci (CNS) (4.2%) and Enterobacteriaceae (8.2%). The mean rates of susceptibility to commonly prescribed drugs are ampicillin 35.5%, cefazolin 89.1%, ciprofloxacin 85.7%, and trimethoprim/sulphamethoxazole (TMP/SMX) 62.1%. Regionally, resistance to TMP/SMX among E. coli now exceeds 30% in all regions. The high prevalence of resistance among uropathogens requires on going surveillance to ensure the provision of effective empirical therapy for acute uncomplicated cystitis.

Original language	English
Pages (from-to)	61-64
Number of pages	4
Journal	International Journal of Antimicrobial Agents
Volume	24
Issue number	SUPPL. 1
DOIs	https://doi.org/10.1016/j.ijantimicag.2004.02.012
Publication status	Published - 2004 Sept
Externally published	Yes

Bibliographical note

Funding Information:
We would like to thank the Korean Urological Association and the Bayer Health Care (Seoul, Korea) for supporting this study. We also thank Samkwang Reference Laboratories for contributing valuable data, and Mizmedi hospital and Dr. Heon Young Kwon from Kwon’s urological clinic for providing data on the UTIs for the first-line clinic.

Keywords

Antimicrobial susceptibility
Ciprofloxacin
Trimethoprim/sulphamethoxazole
Uncomplicated cystitis

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases
Pharmacology (medical)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.ijantimicag.2004.02.012

Cite this

Lee, S. J., Lee, S. D., Cho, I. R., Sim, B. S., Lee, J. G., Kim, C. S., Kim, M. E., Cho, Y. H., & Woo, Y. N. (2004). Antimicrobial susceptibility of uropathogens causing acute uncomplicated cystitis in female outpatients in South Korea: A multicentre study in 2002. International Journal of Antimicrobial Agents, 24(SUPPL. 1), 61-64. https://doi.org/10.1016/j.ijantimicag.2004.02.012

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title = "Antimicrobial susceptibility of uropathogens causing acute uncomplicated cystitis in female outpatients in South Korea: A multicentre study in 2002",

abstract = "The objective of this study was to obtain data on the susceptibility of pathogens responsible for acute uncomplicated cystitis in South Korea to currently used antimicrobial agents. A total of 239 isolates were obtained from female outpatients with acute uncomplicated cystitis. The most prevalent causative organism was Escherichia coli (79.9%), followed by coagulase-negative staphylococci (CNS) (4.2%) and Enterobacteriaceae (8.2%). The mean rates of susceptibility to commonly prescribed drugs are ampicillin 35.5%, cefazolin 89.1%, ciprofloxacin 85.7%, and trimethoprim/sulphamethoxazole (TMP/SMX) 62.1%. Regionally, resistance to TMP/SMX among E. coli now exceeds 30% in all regions. The high prevalence of resistance among uropathogens requires on going surveillance to ensure the provision of effective empirical therapy for acute uncomplicated cystitis.",

keywords = "Antimicrobial susceptibility, Ciprofloxacin, Trimethoprim/sulphamethoxazole, Uncomplicated cystitis",

author = "Lee, {Seung Ju} and Lee, {Sang Don} and Cho, {In Rae} and Sim, {Bong Suck} and Lee, {Jeong Gu} and Kim, {Chul Sung} and Kim, {Min Eui} and Cho, {Yong Hyun} and Woo, {Young Nam}",

note = "Funding Information: We would like to thank the Korean Urological Association and the Bayer Health Care (Seoul, Korea) for supporting this study. We also thank Samkwang Reference Laboratories for contributing valuable data, and Mizmedi hospital and Dr. Heon Young Kwon from Kwon{\textquoteright}s urological clinic for providing data on the UTIs for the first-line clinic.",

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doi = "10.1016/j.ijantimicag.2004.02.012",

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AU - Cho, Yong Hyun

AU - Woo, Young Nam

N1 - Funding Information: We would like to thank the Korean Urological Association and the Bayer Health Care (Seoul, Korea) for supporting this study. We also thank Samkwang Reference Laboratories for contributing valuable data, and Mizmedi hospital and Dr. Heon Young Kwon from Kwon’s urological clinic for providing data on the UTIs for the first-line clinic.

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N2 - The objective of this study was to obtain data on the susceptibility of pathogens responsible for acute uncomplicated cystitis in South Korea to currently used antimicrobial agents. A total of 239 isolates were obtained from female outpatients with acute uncomplicated cystitis. The most prevalent causative organism was Escherichia coli (79.9%), followed by coagulase-negative staphylococci (CNS) (4.2%) and Enterobacteriaceae (8.2%). The mean rates of susceptibility to commonly prescribed drugs are ampicillin 35.5%, cefazolin 89.1%, ciprofloxacin 85.7%, and trimethoprim/sulphamethoxazole (TMP/SMX) 62.1%. Regionally, resistance to TMP/SMX among E. coli now exceeds 30% in all regions. The high prevalence of resistance among uropathogens requires on going surveillance to ensure the provision of effective empirical therapy for acute uncomplicated cystitis.

AB - The objective of this study was to obtain data on the susceptibility of pathogens responsible for acute uncomplicated cystitis in South Korea to currently used antimicrobial agents. A total of 239 isolates were obtained from female outpatients with acute uncomplicated cystitis. The most prevalent causative organism was Escherichia coli (79.9%), followed by coagulase-negative staphylococci (CNS) (4.2%) and Enterobacteriaceae (8.2%). The mean rates of susceptibility to commonly prescribed drugs are ampicillin 35.5%, cefazolin 89.1%, ciprofloxacin 85.7%, and trimethoprim/sulphamethoxazole (TMP/SMX) 62.1%. Regionally, resistance to TMP/SMX among E. coli now exceeds 30% in all regions. The high prevalence of resistance among uropathogens requires on going surveillance to ensure the provision of effective empirical therapy for acute uncomplicated cystitis.

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Antimicrobial susceptibility of uropathogens causing acute uncomplicated cystitis in female outpatients in South Korea: A multicentre study in 2002

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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