Antioxidant activities of fucoidan degraded by gamma irradiation and acidic hydrolysis

Sangyong Lim; Jong il Choi; Hyun Park

doi:10.1016/j.radphyschem.2014.12.008

Antioxidant activities of fucoidan degraded by gamma irradiation and acidic hydrolysis

Sangyong Lim, Jong il Choi, Hyun Park

Research output: Contribution to journal › Article › peer-review

25 Citations (Scopus)

Abstract

Low molecular weight fucoidan, prepared by radical degradation using gamma ray was investigated for its antioxidant activities with different assay methods. As the molecular weight of fucoidan decreased with a higher absorbed dose, ferric-reducing antioxidant power values increased, but β-carotene bleaching inhibition did not change significantly. The antioxidant activity of acid-degraded fucoidan was also examined to investigate the effect of different degradation methods. At the same molecular weight, fucoidan degraded by gamma irradiation showed higher 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity than that observed with the acidic method. This result reveals that in addition to molecular weight, the degradation method affects the antioxidant activity of fucoidan.

Original language	English
Pages (from-to)	23-26
Number of pages	4
Journal	Radiation Physics and Chemistry
Volume	109
DOIs	https://doi.org/10.1016/j.radphyschem.2014.12.008
Publication status	Published - 2015 Apr 1
Externally published	Yes

Bibliographical note

Funding Information:
This research was supported by Golden Seed Project, Ministry of Oceans and Fisheries (213004-04-2-SBA30), by the Nuclear R&D program of the Ministry of Science, ICT & Future Planning, by the research supporting program by Chonnam National University 2013, and by the Antarctic organisms: Cold-Adaptation Mechanisms and its application grant (PE14070) funded by the Korea Polar Research Institute.

Publisher Copyright:
© 2014 Elsevier Ltd.

Keywords

Acid hydrolysis
Antioxidant
Fucoidan
Gamma irradiation

ASJC Scopus subject areas

Radiation

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10.1016/j.radphyschem.2014.12.008

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title = "Antioxidant activities of fucoidan degraded by gamma irradiation and acidic hydrolysis",

abstract = "Low molecular weight fucoidan, prepared by radical degradation using gamma ray was investigated for its antioxidant activities with different assay methods. As the molecular weight of fucoidan decreased with a higher absorbed dose, ferric-reducing antioxidant power values increased, but β-carotene bleaching inhibition did not change significantly. The antioxidant activity of acid-degraded fucoidan was also examined to investigate the effect of different degradation methods. At the same molecular weight, fucoidan degraded by gamma irradiation showed higher 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity than that observed with the acidic method. This result reveals that in addition to molecular weight, the degradation method affects the antioxidant activity of fucoidan.",

keywords = "Acid hydrolysis, Antioxidant, Fucoidan, Gamma irradiation",

author = "Sangyong Lim and Choi, {Jong il} and Hyun Park",

note = "Funding Information: This research was supported by Golden Seed Project, Ministry of Oceans and Fisheries (213004-04-2-SBA30), by the Nuclear R&D program of the Ministry of Science, ICT & Future Planning, by the research supporting program by Chonnam National University 2013, and by the Antarctic organisms: Cold-Adaptation Mechanisms and its application grant (PE14070) funded by the Korea Polar Research Institute. Publisher Copyright: {\textcopyright} 2014 Elsevier Ltd.",

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doi = "10.1016/j.radphyschem.2014.12.008",

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AU - Lim, Sangyong

AU - Choi, Jong il

AU - Park, Hyun

N1 - Funding Information: This research was supported by Golden Seed Project, Ministry of Oceans and Fisheries (213004-04-2-SBA30), by the Nuclear R&D program of the Ministry of Science, ICT & Future Planning, by the research supporting program by Chonnam National University 2013, and by the Antarctic organisms: Cold-Adaptation Mechanisms and its application grant (PE14070) funded by the Korea Polar Research Institute. Publisher Copyright: © 2014 Elsevier Ltd.

PY - 2015/4/1

Y1 - 2015/4/1

N2 - Low molecular weight fucoidan, prepared by radical degradation using gamma ray was investigated for its antioxidant activities with different assay methods. As the molecular weight of fucoidan decreased with a higher absorbed dose, ferric-reducing antioxidant power values increased, but β-carotene bleaching inhibition did not change significantly. The antioxidant activity of acid-degraded fucoidan was also examined to investigate the effect of different degradation methods. At the same molecular weight, fucoidan degraded by gamma irradiation showed higher 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity than that observed with the acidic method. This result reveals that in addition to molecular weight, the degradation method affects the antioxidant activity of fucoidan.

AB - Low molecular weight fucoidan, prepared by radical degradation using gamma ray was investigated for its antioxidant activities with different assay methods. As the molecular weight of fucoidan decreased with a higher absorbed dose, ferric-reducing antioxidant power values increased, but β-carotene bleaching inhibition did not change significantly. The antioxidant activity of acid-degraded fucoidan was also examined to investigate the effect of different degradation methods. At the same molecular weight, fucoidan degraded by gamma irradiation showed higher 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity than that observed with the acidic method. This result reveals that in addition to molecular weight, the degradation method affects the antioxidant activity of fucoidan.

KW - Acid hydrolysis

KW - Antioxidant

KW - Fucoidan

KW - Gamma irradiation

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DO - 10.1016/j.radphyschem.2014.12.008

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AN - SCOPUS:84919915770

SN - 0969-806X

VL - 109

SP - 23

EP - 26

JO - Radiation Physics and Chemistry

JF - Radiation Physics and Chemistry

ER -

Antioxidant activities of fucoidan degraded by gamma irradiation and acidic hydrolysis

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

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