APOE ε2/ε4 polymorphism and cerebral microbleeds on gradient-echo MRI

M. Kim; H. J. Bae; J. Lee; L. Kang; S. Lee; S. Kim; J. E. Lee; K. M. Lee; B. W. Yoon; O. Kwon; J. S. Koo; B. K. Kim

doi:10.1212/01.wnl.0000183311.48144.7f

APOE ε2/ε4 polymorphism and cerebral microbleeds on gradient-echo MRI

M. Kim, H. J. Bae, J. Lee, L. Kang, S. Lee, S. Kim, J. E. Lee, K. M. Lee, B. W. Yoon, O. Kwon, J. S. Koo, B. K. Kim

Research output: Contribution to journal › Article › peer-review

31 Citations (Scopus)

Abstract

The association of APOE genotypes with cerebral microbleeds (CMBs) was examined on the basis of the location of CMBs in 414 patients who were admitted primarily because of stroke. With respect to possession of the ε2 or ε4 allele, the adjusted odds ratio was 1.94 (1.05 to 3.58) for lobar CMBs but 1.21 (0.69 to 2.11) for nonlobar CMBs. This suggests that the pathogenesis of CMBs may differ depending on their location.

Original language	English
Pages (from-to)	1474-1475
Number of pages	2
Journal	Neurology
Volume	65
Issue number	9
DOIs	https://doi.org/10.1212/01.wnl.0000183311.48144.7f
Publication status	Published - 2005 Nov 8
Externally published	Yes

ASJC Scopus subject areas

Clinical Neurology

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abstract = "The association of APOE genotypes with cerebral microbleeds (CMBs) was examined on the basis of the location of CMBs in 414 patients who were admitted primarily because of stroke. With respect to possession of the ε2 or ε4 allele, the adjusted odds ratio was 1.94 (1.05 to 3.58) for lobar CMBs but 1.21 (0.69 to 2.11) for nonlobar CMBs. This suggests that the pathogenesis of CMBs may differ depending on their location.",

author = "M. Kim and Bae, {H. J.} and J. Lee and L. Kang and S. Lee and S. Kim and Lee, {J. E.} and Lee, {K. M.} and Yoon, {B. W.} and O. Kwon and Koo, {J. S.} and Kim, {B. K.}",

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AU - Kim, M.

AU - Bae, H. J.

AU - Lee, J.

AU - Kang, L.

AU - Lee, S.

AU - Kim, S.

AU - Lee, J. E.

AU - Lee, K. M.

AU - Yoon, B. W.

AU - Kwon, O.

AU - Koo, J. S.

AU - Kim, B. K.

PY - 2005/11/8

Y1 - 2005/11/8

N2 - The association of APOE genotypes with cerebral microbleeds (CMBs) was examined on the basis of the location of CMBs in 414 patients who were admitted primarily because of stroke. With respect to possession of the ε2 or ε4 allele, the adjusted odds ratio was 1.94 (1.05 to 3.58) for lobar CMBs but 1.21 (0.69 to 2.11) for nonlobar CMBs. This suggests that the pathogenesis of CMBs may differ depending on their location.

AB - The association of APOE genotypes with cerebral microbleeds (CMBs) was examined on the basis of the location of CMBs in 414 patients who were admitted primarily because of stroke. With respect to possession of the ε2 or ε4 allele, the adjusted odds ratio was 1.94 (1.05 to 3.58) for lobar CMBs but 1.21 (0.69 to 2.11) for nonlobar CMBs. This suggests that the pathogenesis of CMBs may differ depending on their location.

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ER -

APOE ε2/ε4 polymorphism and cerebral microbleeds on gradient-echo MRI

Abstract

ASJC Scopus subject areas

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