Application of the Quality-by-Design (QbD) Approach for Erythropoietin Alpha Purification

Keyphrases

• Acceptance Range 50%
• Aggregate Content 50%
• Biopharmaceutical Agent 50%
• Biopharmaceutical Manufacturing 50%
• By Design 100%
• Charge Isomers 50%
• Comparison with Data 50%
• Contour Plots 50%
• Critical Quality Attributes 100%
• Deoxynucleotides 50%
• Design Space 50%
• Downscaling 50%
• Endotoxin 50%
• Erythropoietin 50%
• Erythropoietin Alfa 100%
• Host Cell 50%
• Host Cell Proteins 50%
• Large-scale Production 50%
• Loading Amount 50%
• Manufacturing Quality 50%
• Monte Carlo Simulation 50%
• N-glycan 50%
• Optimization Analysis 50%
• Performance Indicators 50%
• PH Buffer 50%
• Pharmaceutical Industry 50%
• Process Characterization 100%
• Process Improving 50%
• Production Facilities 50%
• Purification Process 50%
• Quality Attributes 50%
• Quality Performance 50%
• Regression Analysis 50%
• Relative Content 50%
• Statistical Prediction Model 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Biopharmaceutical 100%
• Buffer 33%
• Cell Protein 33%
• Deoxyribonucleotide 33%
• Endotoxin 33%
• Erythropoietin 100%
• Glycan 33%

Food Science

• Erythropoietin 100%
• Quality Attribute 100%