Applications and advances in bioelectronic noses for odour sensing

Tran Thi Dung, Yunkwang Oh, Seon Jin Choi, Il Doo Kim, Min Kyu Oh, Moonil Kim

Research output: Contribution to journalReview articlepeer-review

68 Citations (Scopus)


A bioelectronic nose, an intelligent chemical sensor array system coupled with bio-receptors to identify gases and vapours, resembles mammalian olfaction by which many vertebrates can sniff out volatile organic compounds (VOCs) sensitively and specifically even at very low concentrations. Olfaction is undertaken by the olfactory system, which detects odorants that are inhaled through the nose where they come into contact with the olfactory epithelium containing olfactory receptors (ORs). Because of its ability to mimic biological olfaction, a bio-inspired electronic nose has been used to detect a variety of important compounds in complex environments. Recently, biosensor systems have been introduced that combine nanoelectronic technology and olfactory receptors themselves as a source of capturing elements for biosensing. In this article, we will present the latest advances in bioelectronic nose technology mimicking the olfactory system, including biological recognition elements, emerging detection systems, production and immobilization of sensing elements on sensor surface, and applications of bioelectronic noses. Furthermore, current research trends and future challenges in this field will be discussed.

Original languageEnglish
Article number103
JournalSensors (Switzerland)
Issue number1
Publication statusPublished - 2018 Jan

Bibliographical note

Funding Information:
Acknowledgments: This work was equally supported by the BionNano Health-Guard Research Center as Global Frontier Project (H-GUARD 2016941340) and the Korea Research Institute of Bioscience and Biotechnology (KRIBB) Initiative Research Program.

Publisher Copyright:
© 2018 by the authors. Licensee MDPI, Basel, Switzerland.


  • Bioelectronic nose
  • Biosensor
  • OR
  • Odour analysis
  • Olfactory receptor

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Atomic and Molecular Physics, and Optics
  • Instrumentation
  • Electrical and Electronic Engineering


Dive into the research topics of 'Applications and advances in bioelectronic noses for odour sensing'. Together they form a unique fingerprint.

Cite this