Aptamer-based sandwich-type biosensors

Ho Bin Seo, Man Bock Gu

Research output: Contribution to journalReview articlepeer-review

94 Citations (Scopus)


Sandwich-type biosensor platforms have drawn lots of attentions due to its superior features, compared to other platforms, in terms of its stable and reproducible responses and easy enhancement in the detection sensitivity. The sandwich-type assays can be developed by utilizing a pair of receptors, which bind to the different sites of the same target. In this mini-review paper, the sandwich-type biosensors using either pairs of aptamers or aptamer-antibody pairs are reviewed in terms of its targets and platforms, the schematic designs, and their analytical performance.

Original languageEnglish
Article number11
JournalJournal of Biological Engineering
Issue number1
Publication statusPublished - 2017 Mar 13


  • A pair of aptamer
  • Aptamer-antibody complex
  • Aptasensor
  • Sandwich-type aptasensor
  • Sandwich-type biosensors

ASJC Scopus subject areas

  • Environmental Engineering
  • Biomedical Engineering
  • Molecular Biology
  • Cell Biology


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