Abstract
Sandwich-type biosensor platforms have drawn lots of attentions due to its superior features, compared to other platforms, in terms of its stable and reproducible responses and easy enhancement in the detection sensitivity. The sandwich-type assays can be developed by utilizing a pair of receptors, which bind to the different sites of the same target. In this mini-review paper, the sandwich-type biosensors using either pairs of aptamers or aptamer-antibody pairs are reviewed in terms of its targets and platforms, the schematic designs, and their analytical performance.
| Original language | English |
|---|---|
| Article number | 11 |
| Journal | Journal of Biological Engineering |
| Volume | 11 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 2017 Mar 13 |
Bibliographical note
Funding Information:Not applicable. Funding This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIP) (No.2016R1E1A2020541) and the National Research Foundation of Korea (NRF) grant funded by the Korean government (MEST) (No.2016R1A2B3011422) and a grant of the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health & Welfare, Republic of Korea (grant number: HI16C0220). In addition, Mr. Ho Bin Seo, PhD student, was financially supported for visiting research at the University of Arizona during 6 months by BK21 PLUS, Korea University.
Publisher Copyright:
© 2017 The Author(s).
Keywords
- A pair of aptamer
- Aptamer-antibody complex
- Aptasensor
- Sandwich-type aptasensor
- Sandwich-type biosensors
ASJC Scopus subject areas
- Environmental Engineering
- Biomedical Engineering
- Molecular Biology
- Cell Biology