Are metabolic risk factors and target organ damage more frequent in masked hypertension than in white coat hypertension

Hyun Ju Yoon, Youngkeun Ahn, Jeong Bae Park, Chang Gyu Park, Ho Joong Youn, Dong Ju Choi, Joon Han Shin, Dong Woon Kim, Se Joong Rim, Jang Ho Bae

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9 Citations (Scopus)


Patients with masked hypertension (MH) tend to have a higher risk than those with white-coat hypertension (WCH). Therefore, we evaluated the characteristics of MH and WCH in Korean patients receiving medical treatment for hypertension. We enrolled 1019 outpatients (56 ± 10 y, 488 males) with diagnosed hypertension who had not changed oral anti-hypertensive medication for 6 months. Clinic blood pressure (CBP) was checked by a nurse and doctor twice per visit. Home BP (HBP) was checked every morning and evening for 1 week. In the MH patients, mean CBP was 13080 mmHg, whereas HBP was 13786 mmHg. In the WCH patients, mean CBP was 14986 mmHg by physician and 14385 mmHg by nurse and mean HBP was 12475 mmHg. Age and gender did not differ between the groups. Waist and hip circumferences and the level of fasting glucose were higher in patients with MH than in patients with WCH (p 0.008, 0.016, 0.009, respectively). Metabolic risk factors were more frequent in patients with WCH, MH, and uncontrolled hypertension than in patients with controlled hypertension. The incidence of metabolic risk factors, however, did not differ between patients with WCH and MH. Heart damage was more frequent in MH than in WCH (p 0.03). The incidence of metabolic risk factors did not differ between patients with WCH and those with MH. Target organ damage was more closely related to MH than to WCH. Home BP measurement was a useful tool for discriminating WCH and MH in patients with hypertension.

Original languageEnglish
Pages (from-to)480-485
Number of pages6
JournalClinical and Experimental Hypertension
Issue number7
Publication statusPublished - 2010 Nov
Externally publishedYes

Bibliographical note

Funding Information:
This work was supported by a grant of the National Research Foundation of Korea Grant funded by the Korean Government (MEST), Republic of Korea (2010-0020261 and 2009 0076358), and the Korea Healthcare Technology R&D Project, Ministry for Health, Welfare & Family Affairs, Republic of Korea (A084869).


  • Hypertension
  • Metabolic risk factors
  • Target organ damage

ASJC Scopus subject areas

  • Internal Medicine
  • Physiology


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